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[传染性单核细胞增多症及其他病毒感染患者中自然杀伤细胞的功能活性]

[The functional activity of the natural killers in patients with infectious mononucleosis and other viral infections].

作者信息

Zverkova A S, Faktorova E I

出版信息

Vrach Delo. 1990 Jun(6):107-10.

PMID:2399702
Abstract

The natural killer activity (NKA) and content of large granule-containing lymphocytes (LGL) were determined in 50 patients with infectious mononucleosis and in 36 patients with other viral infections. Results indicate that in 27 of 50 patients with infectious mononucleosis the number of LGL was less than 5% or equalled O. In 12 patients with infectious mononucleosis the number of LGL was 5% and in 11 children it was 5-20%. In children with different viral infections not related to the Epstein-Barr virus the number of LGL was below normal values. The NKA corresponded to the quantitative indices of LGL as well as the severity of the clinical condition.

摘要

对50例传染性单核细胞增多症患者和36例其他病毒感染患者测定了自然杀伤活性(NKA)和含大颗粒淋巴细胞(LGL)的含量。结果表明,50例传染性单核细胞增多症患者中,27例LGL数量少于5%或等于0。12例传染性单核细胞增多症患者LGL数量为5%,11例儿童患者LGL数量为5%-20%。在与爱泼斯坦-巴尔病毒无关的不同病毒感染儿童中,LGL数量低于正常值。NKA与LGL的定量指标以及临床病情严重程度相符。

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