• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

老年人胫骨骨干骨折的转归。

The outcome of tibial diaphyseal fractures in the elderly.

机构信息

Edinburgh Orthopaedic Trauma Unit, Royal Infirmary of Edinburgh, 51 Little France Crescent, Edinburgh EH16 4SU, UK.

出版信息

Bone Joint J. 2013 Sep;95-B(9):1255-62. doi: 10.1302/0301-620X.95B9.31112.

DOI:10.1302/0301-620X.95B9.31112
PMID:23997142
Abstract

We describe the outcome of tibial diaphyseal fractures in the elderly (≥ 65 years of age). We prospectively followed 233 fractures in 225 elderly patients over a minimum ten-year period. Demographic and descriptive data were acquired from a prospective trauma database. Mortality status was obtained from the General Register Office database for Scotland. Diaphyseal fractures of the tibia in the elderly occurred predominantly in women (73%) and after a fall (61%). During the study period the incidence of these fractures decreased, nearly halving in number. The 120-day and one-year unadjusted mortality rates were 17% and 27%, respectively, and were significantly greater in patients with an open fracture (p < 0.001). The overall standardised mortality ratio (SMR) was significantly increased (SMR 4.4, p < 0.001) relative to the population at risk, and was greatest for elderly women (SMR 8.1, p < 0.001). These frailer patients had more severe injuries, with an increased rate of open fractures (30%), and suffered a greater rate of nonunion (10%). Tibial diaphyseal fractures in the elderly are most common in women after a fall, are more likely to be open than in the rest of the population, and are associated with a high incidence of nonunion and mortality.

摘要

我们描述了老年人(≥65 岁)胫骨骨干骨折的结果。我们前瞻性随访了 225 名老年患者的 233 例骨折,随访时间至少为 10 年。人口统计学和描述性数据来自前瞻性创伤数据库。苏格兰总登记处数据库获得了死亡率状况。老年人胫骨骨干骨折主要发生在女性(73%)和跌倒后(61%)。在研究期间,这些骨折的发生率下降,几乎减少了一半。120 天和 1 年未调整的死亡率分别为 17%和 27%,开放性骨折患者的死亡率显著更高(p < 0.001)。总体标准化死亡率(SMR)显著增加(SMR 4.4,p < 0.001),与危险人群相比,这在老年女性中更为明显(SMR 8.1,p < 0.001)。这些更脆弱的患者受伤更严重,开放性骨折的发生率更高(30%),且不愈合的发生率更高(10%)。老年人胫骨骨干骨折最常见于女性跌倒后,比其他人群更可能是开放性骨折,并且与高发生率的不愈合和死亡率相关。

相似文献

1
The outcome of tibial diaphyseal fractures in the elderly.老年人胫骨骨干骨折的转归。
Bone Joint J. 2013 Sep;95-B(9):1255-62. doi: 10.1302/0301-620X.95B9.31112.
2
Elderly tibial shaft fractures: Open fractures are not associated with increased mortality rates.老年胫骨骨干骨折:开放性骨折与死亡率增加无关。
Injury. 2010 Jun;41(6):620-3. doi: 10.1016/j.injury.2009.12.013. Epub 2010 Feb 1.
3
Clinical experience with reamed locked nails for close and open comminuted tibial diaphyseal fractures: a review of 50 consecutive cases.
Med J Malaysia. 2000 Sep;55 Suppl C:59-67.
4
Compartment pressures of the leg following intramedullary fixation of the tibia.胫骨髓内固定术后小腿骨筋膜室压力
Orthop Rev. 1992 Oct;21(10):1221-5.
5
Reamed versus minimally reamed nailing: a prospectively randomised study of 100 patients with closed fractures of the tibia.扩髓与微扩髓髓内钉固定治疗胫骨闭合性骨折:100 例前瞻性随机研究。
Injury. 2011 Sep;42 Suppl 4:S17-21. doi: 10.1016/S0020-1383(11)70007-9.
6
Randomized, prospective comparison of plate versus intramedullary nail fixation for distal tibia shaft fractures.随机、前瞻性比较钢板与髓内钉固定治疗胫骨骨干远端骨折。
J Orthop Trauma. 2011 Dec;25(12):736-41. doi: 10.1097/BOT.0b013e318213f709.
7
Factors affecting fracture healing after intramedullary nailing of the tibial diaphysis for closed and grade I open fractures.
J Bone Joint Surg Br. 2006 Feb;88(2):227-31. doi: 10.1302/0301-620X.88B2.16456.
8
[Segmental tibia fractures: a critical retrospective analysis of 49 cases].[胫骨节段性骨折:49例病例的批判性回顾分析]
Rev Chir Orthop Reparatrice Appar Mot. 2003 Sep;89(5):423-32.
9
The segmental tibial fracture.胫骨节段性骨折。
Clin Orthop Relat Res. 1992 Aug(281):204-7.
10
Extra-articular fractures of the proximal tibial diaphysis: their epidemiology, management and outcome.胫骨近端骨干关节外骨折:其流行病学、治疗及预后
J R Coll Surg Edinb. 1997 Oct;42(5):334-8.

引用本文的文献

1
Demographic Differences in the Surgical Management of Tibial Shaft Fractures: A Retrospective Study.胫骨干骨折手术治疗中的人口统计学差异:一项回顾性研究
Cureus. 2025 Feb 12;17(2):e78917. doi: 10.7759/cureus.78917. eCollection 2025 Feb.
2
Comparison of Radiographic Outcomes Assessed via the Radiographic Union Scale for Tibial Fractures and Alkaline Phosphatase Levels during the Tibial Healing Process: A Series of Case Reports.通过胫骨骨折影像学愈合量表评估的影像学结果与胫骨愈合过程中碱性磷酸酶水平的比较:系列病例报告
Biology (Basel). 2024 Jun 3;13(6):407. doi: 10.3390/biology13060407.
3
The impact of age and sex on the inflammatory response during bone fracture healing.
年龄和性别对骨折愈合过程中炎症反应的影响。
JBMR Plus. 2024 Feb 22;8(5):ziae023. doi: 10.1093/jbmrpl/ziae023. eCollection 2024 May.
4
Estrogen deficiency impedes fracture healing despite eliminating the excessive absorption of the posterior callus in a semi-fixed distal tibial fracture mouse model.雌激素缺乏会阻碍骨折愈合,尽管它能消除半固定胫骨远端骨折小鼠模型中后骨痂的过度吸收。
BMC Musculoskelet Disord. 2023 Oct 10;24(1):803. doi: 10.1186/s12891-023-06929-2.
5
Fracture healing is delayed in the absence of gasdermin-interleukin-1 signaling.缺乏 GSDMD-IL1 信号会延迟骨折愈合。
Elife. 2022 Mar 4;11:e75753. doi: 10.7554/eLife.75753.
6
An Early Experience with a Novel Technique of Total Knee Arthroplasty for Osteoarthritic Knee with Coexistent Traumatic Tibia Diaphysis Fracture.一种用于治疗合并创伤性胫骨干骨折的骨关节炎膝关节的全膝关节置换新技术的早期经验。
Indian J Orthop. 2021 Apr 22;56(1):110-115. doi: 10.1007/s43465-021-00406-5. eCollection 2022 Jan.
7
Mortality and morbidity following operative management of tibial shaft fractures in octogenarians.80 岁以上老年人胫骨骨干骨折手术治疗后的死亡率和发病率。
Eur J Orthop Surg Traumatol. 2023 Feb;33(2):299-304. doi: 10.1007/s00590-021-03180-0. Epub 2022 Jan 15.
8
Open tibia/fibula in the elderly: A retrospective cohort study.老年人开放性胫腓骨骨折:一项回顾性队列研究。
JPRAS Open. 2021 Oct 1;31:1-9. doi: 10.1016/j.jpra.2021.09.003. eCollection 2022 Mar.
9
Wnt/β-catenin signalling promotes more effective fracture healing in aged mice than in adult mice by inducing angiogenesis and cell differentiation.Wnt/β-catenin 信号通路通过诱导血管生成和细胞分化,促进老年小鼠比成年小鼠更有效地愈合骨折。
Sci Prog. 2021 Apr-Jun;104(2):368504211013223. doi: 10.1177/00368504211013223.
10
Gentamicin-Coated Tibia Nail in Fractures and Nonunion to Reduce Fracture-Related Infections: A Systematic Review.庆大霉素涂层胫骨钉治疗骨折和骨折不愈合以减少与骨折相关的感染:系统评价。
Molecules. 2020 Nov 23;25(22):5471. doi: 10.3390/molecules25225471.