Kim Na-Mi, So Seung-Ho, Lee Sung-Gae, Song Jung-Eun, Seo Dong-Soo, Lee Jong-Soo
KT&G Co. Central Research Institute, Daejeon 305-345, Korea.
Mycobiology. 2008 Sep;36(3):148-51. doi: 10.4489/MYCO.2008.36.3.148. Epub 2008 Sep 30.
A novel biomass was prepared from Pichia anomala KCCM 11473, which grew well in ginseng-steaming effluent (GSE), and its physiological functionalities and enzyme activities were determined. When the strain was cultured in the GSE (pH 6.0) at 30℃ for 48 h, 1.6 mg of biomass per ml-cultures was produced. The cell-free extract of the biomass showed high antihypertensive angiotensin I-converting enzyme inhibitory activity of 72.0% and anticholesteromia HMG-CoA reductase inhibitory activity of 46.5%. The cell-free extract also showed 13.0 U per ml and 8.5 U per ml of neutral protease activity and alkaline protease, respectively.
从异常毕赤酵母KCCM 11473制备了一种新型生物质,该酵母在人参蒸煮废水(GSE)中生长良好,并测定了其生理功能和酶活性。当该菌株在30℃的GSE(pH 6.0)中培养48小时时,每毫升培养物产生1.6毫克生物质。该生物质的无细胞提取物显示出72.0%的高抗高血压血管紧张素I转换酶抑制活性和46.5%的抗胆固醇HMG-CoA还原酶抑制活性。无细胞提取物还分别显示出每毫升13.0 U和8.5 U的中性蛋白酶活性和碱性蛋白酶活性。