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鼻及鼻窦病变的组织病理学研究

Histopathological study of lesions of nose and paranasal sinuses.

作者信息

M Kulkarni Aparna, G Mudholkar Vishal, S Acharya Abhijit, V Ramteke Ravindra

机构信息

Department of Pathology, RCSM Government Medical College & CPR Hospital, Kolhapur, Maharashtra 416 002 India.

出版信息

Indian J Otolaryngol Head Neck Surg. 2012 Sep;64(3):275-9. doi: 10.1007/s12070-011-0286-7. Epub 2011 Sep 10.

Abstract

(1) To study the incidence of benign and malignant lesions of nose and paranasal sinuses (PNS). (2) To study various lesions in reference to sex differences and symptomatology. (3) To compare the findings of the study with other authors. The study was conducted over a period of 7 years both retrospectively and prospectively. The formalin fixed specimens were received with complete clinical and radiological features. Routine gross examination and required number of sections were taken and stained with hematoxylin and eosin. Periodic acid Schiffs and reticulin stains were used wherever necessary. The incidence of lesions in nasal cavity (NC) and PNS was 16.71 cases per year, non-neoplastic lesions constituted 86% of these cases and their incidence was 14.42% and neoplastic lesions constituted 12%. All the cases were carefully examined histopathologically and it was found that the region was affected by variety of lesions. Among 117 cases, 101 were non-neoplastic and 16 were neoplastic. The commonest site was NC, followed by PNS. They occur commonly in second and third decades with predominance in males. Amongst the non-inflammatory lesion, nasal polyp is the commonest lesion followed by rhinoscleroma and rhinosporidiosis. The common age group is second and third decades, with male predominance. Amongst benign neoplastic lesions capillary haemangioma was common followed by inverted papilloma. The common age group is second and third decades, with male predominance. Malignant lesions were comparatively less to that of benign lesions.

摘要

(1) 研究鼻及鼻窦(PNS)良性和恶性病变的发生率。(2) 研究各种病变的性别差异和症状学。(3) 将本研究结果与其他作者的进行比较。本研究回顾性和前瞻性地进行了7年。接收的福尔马林固定标本具有完整的临床和放射学特征。进行常规大体检查并取所需数量的切片,用苏木精和伊红染色。必要时使用过碘酸希夫染色和网状纤维染色。鼻腔(NC)和PNS病变的发生率为每年16.71例,其中非肿瘤性病变占这些病例的86%,其发生率为14.42%,肿瘤性病变占12%。所有病例均进行了仔细的组织病理学检查,发现该区域受多种病变影响。117例中,101例为非肿瘤性病变,16例为肿瘤性病变。最常见的部位是NC,其次是PNS。它们常见于第二和第三个十年,男性居多。在非炎性病变中,鼻息肉是最常见的病变,其次是鼻硬结病和鼻孢子虫病。常见年龄组为第二和第三个十年,男性居多。在良性肿瘤性病变中,毛细血管瘤常见,其次是内翻性乳头状瘤。常见年龄组为第二和第三个十年,男性居多。恶性病变相对良性病变较少。

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