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小儿尖锐湿疣

Pediatric condyloma acuminata.

作者信息

Varma Selina, Lathrop Eva, Haddad Lisa B

机构信息

Emory University School of Medicine, Atlanta, GA.

出版信息

J Pediatr Adolesc Gynecol. 2013 Dec;26(6):e121-2. doi: 10.1016/j.jpag.2013.03.017. Epub 2013 Aug 31.

Abstract

BACKGROUND

Condyloma acuminata are caused by human papilloma virus (HPV) 6 and 11 and most commonly present in the anogenital region. Most transmission among adults is via sexual transmission, but HPV and resulting anogenital warts in pediatric populations may be a result of perinatal vertical transmission, indirect transmission through contaminated objects or surfaces, autoinoculation, or sexual transmission.

CASE

A 9-year-old premenarchal female presented with multiple perianal warts. She had no significant medical history, and denied history of any sexual contact, including sexual abuse. The external examination revealed multiple warts in the perianal region, but no lesions, discharge, inflammation, or external signs of trauma were visible. Tests for sexually transmitted infections were all negative. The warts were diagnosed as condyloma acuminata, and were subsequently treated with trichloroacetic acid 80% (TCA) in the provider's office. TCA was applied on 3 separate occasions 2 weeks apart, showing marked improvement at each visit.

SUMMARY/DISCUSSION: While both sexual and nonsexual means of transmission are possible, sexual abuse must always be considered in pediatric cases. It is recommended that investigators proceed delicately, because the investigation can be psychologically damaging for patients and their families. Treatment methods are a unique consideration for pediatric patients, as most options are painful and require multiple office visits. The benefits of self-administration at home must be weighed with the likelihood of patient compliance and need for ongoing evaluation by the provider.

摘要

背景

尖锐湿疣由人乳头瘤病毒(HPV)6型和11型引起,最常见于肛门生殖器区域。成年人之间的传播大多通过性传播,但儿科人群中的HPV及由此导致的肛门生殖器疣可能是围产期垂直传播、通过受污染物体或表面的间接传播、自体接种或性传播的结果。

病例

一名9岁青春期前女性出现多个肛周疣。她没有明显的病史,否认有任何性接触史,包括性虐待史。体格检查发现肛周区域有多个疣,但未见病变、分泌物、炎症或外伤的外部迹象。性传播感染检测均为阴性。这些疣被诊断为尖锐湿疣,随后在医疗机构用80%的三氯乙酸(TCA)进行治疗。TCA分3次分别在相隔2周的时间应用,每次就诊时均显示有明显改善。

总结/讨论:虽然性传播和非性传播途径都有可能,但儿科病例中必须始终考虑性虐待的可能性。建议调查人员谨慎行事,因为调查可能会对患者及其家人造成心理伤害。治疗方法是儿科患者需要特别考虑的问题,因为大多数治疗选择都很痛苦,且需要多次到医疗机构就诊。必须权衡在家自行用药的好处与患者依从性的可能性以及医疗机构持续评估的必要性。

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