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一名已知患有乳腺癌的患者,因肺动静脉畸形导致反常栓塞继发缺血性中风。

Ischaemic stroke secondary to paradoxical emboli through an arteriovenous malformation of the lung in a patient with known breast cancer.

作者信息

Sellon Edward, Ring Alistair, Howlett David

机构信息

Department of Radiology, Eastbourne Hospital, Eastbourne, UK.

出版信息

BMJ Case Rep. 2013 Sep 3;2013:bcr2013008672. doi: 10.1136/bcr-2013-008672.

Abstract

We presented an unusual case of a young woman who suffered an ischaemic stroke while receiving chemotherapy postsurgery for breast cancer. No cause was identified at that time and a year later an incidental pulmonary arteriovenous malformation (PAVM) was diagnosed during an MR review of her breasts. This was confirmed on the CT and she subsequently underwent successful endovascular embolisation. Ischaemic stroke as a presenting symptom of an undiagnosed PAVM or hereditary haemorrhagic telangiectasia is rare. PAVM is a clinically important and treatable cause of ischaemic stroke and should therefore be considered in young patients with ischaemic stroke, with or without concurrent venous thrombotic risk factors. As far as we are aware, this is the first reported incidental finding of PAVM on MR of the breast.

摘要

我们报告了一例不同寻常的病例,一名年轻女性在乳腺癌手术后接受化疗期间发生了缺血性中风。当时未查明病因,一年后在对其乳房进行磁共振复查时诊断出一例偶然发现的肺动静脉畸形(PAVM)。CT检查证实了这一情况,随后她成功接受了血管内栓塞治疗。缺血性中风作为未确诊的PAVM或遗传性出血性毛细血管扩张症的首发症状较为罕见。PAVM是缺血性中风的一个具有临床重要性且可治疗的病因,因此对于患有缺血性中风的年轻患者,无论有无并发静脉血栓形成风险因素,均应考虑该病。据我们所知,这是首次报道在乳房磁共振检查中偶然发现PAVM。

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本文引用的文献

1
Aetiological diagnosis of ischaemic stroke in young adults.
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Stroke after prolonged air travel associated with a pulmonary arteriovenous malformation.
J Neurol Sci. 2010 May 15;292(1-2):99-100. doi: 10.1016/j.jns.2010.02.019. Epub 2010 Mar 16.
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Postgrad Med J. 2002 Apr;78(918):191-7. doi: 10.1136/pmj.78.918.191.

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