Zelner Irene, Koren Gideon
Division of Clinical Pharmacology-Toxicology, Department of Pediatrics, Hospital for Sick Children and University of Toronto, Toronto, Canada.
J Popul Ther Clin Pharmacol. 2013;20(2):e201-6. Epub 2013 Aug 20.
Alcohol (ethanol) consumption in pregnancy is the etiology of fetal alcohol spectrum disorder (FASD), a leading cause of congenital disability worldwide. Hence, any attempt to prevent or manage FASD must start from comprehensive understanding of alcohol consumption by women in general, and by women of reproductive years in particular. This review presents and synthesizes studies conducted worldwide on alcohol consumption by pregnant women, risk factors associated with gestational drinking, as well as doses and definitions of drinking behaviours.
孕期饮酒是胎儿酒精谱系障碍(FASD)的病因,而FASD是全球先天性残疾的主要原因。因此,任何预防或管理FASD的尝试都必须从全面了解一般女性,尤其是育龄女性的饮酒情况开始。本综述展示并综合了全球范围内关于孕妇饮酒、与孕期饮酒相关的风险因素以及饮酒行为的剂量和定义的研究。