氯霉素对斜生栅藻和蛋白核小球藻的急性和慢性毒性效应。
Acute and chronic toxic effects of chloramphenicol on Scenedesmus obliquus and Chlorella pyrenoidosa.
机构信息
State Environmental Protection Key Laboratory of Environmental Risk Assessment and Control on Chemical Process, East China University of Science and Technology, Shanghai 200237, PR China.
出版信息
Water Environ Res. 2013 Aug;85(8):725-32. doi: 10.2175/106143013x13596524515780.
The acute and chronic toxicological effects of Chloramphenicol (CAP) on Scenedesmus obliquus and Chlorella pyrenoidosa are not well understood. The indoor experiments were carried to observe and analyze the CAP induced changes. Results of the observations have showed that CAP exposure could significantly inhibit the growth of Scenedesmus obliquus in almost all the treated groups, while Chlorella pyrenoidosa exhibited less sensitivity. Chlorophyll-a syntheses of Scenedesmus obliquus were all inhibited by CAP exposure, while Chlorella pyrenoidosa displayed obvious stimulation effect. Catalase (CAT) and Superoxide dismutase (SOD) activities of both algae were promoted in all the treatments. The experimental results indicated that the growth and Chlorophyll-a syntheses of Scenedesmus obliquus were more sensitive in response to CAP exposure than that of Chlorella pyrenoidosa. While for CAT and SOD activities, Chlorella pyrenoidosa showed more susceptible. This research provides a basic understanding of CAP toxicity to aquatic organisms.
氯霉素（CAP）对斜生栅藻和蛋白核小球藻的急性和慢性毒理学效应尚未得到很好的理解。进行了室内实验来观察和分析 CAP 引起的变化。观察结果表明，CAP 暴露几乎可以抑制所有处理组中斜生栅藻的生长，而蛋白核小球藻的敏感性较低。CAP 暴露会抑制斜生栅藻的叶绿素-a 合成，而蛋白核小球藻则表现出明显的刺激作用。两种藻类的过氧化氢酶（CAT）和超氧化物歧化酶（SOD）活性均在所有处理中得到促进。实验结果表明，斜生栅藻的生长和叶绿素-a 合成对 CAP 暴露的反应比蛋白核小球藻更为敏感。而对于 CAT 和 SOD 活性，蛋白核小球藻则表现出更高的敏感性。本研究为 CAP 对水生生物的毒性提供了基本的了解。
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