铜催化的富勒烯与脒或酰胺的氧化[3 + 2]反应：富勒烯咪唑或富勒烯恶唑衍生物的制备。

CuI-catalyzed oxidative [3 + 2] reaction of fullerene with amidines or amides using air as the oxidant: preparation of fulleroimidazole or fullerooxazole derivatives.

机构信息

School of Petrochemical Engineering, Changzhou University , Changzhou 213164, P. R. China.

出版信息

Org Lett. 2013 Sep 20;15(18):4650-3. doi: 10.1021/ol401909z. Epub 2013 Sep 4.

DOI:10.1021/ol401909z

Abstract

CuI-catalyzed oxidative reaction of amidines with C60 using air as the oxidant has been exploited for the easy preparation of fulleroimidazole derivatives. Furthermore, this kind of CuI-catalyzed [3 + 2] reaction has also been successfully applied in the synthesis of fullerooxazole derivatives starting from amides for the first time. The substrate scope is broad, and the process is particularly cheap and simple.

摘要

CuI 催化的 amidines 与 C60 的氧化反应，以空气作为氧化剂，用于容易制备富勒烯咪唑衍生物。此外，这种 CuI 催化的 [3 + 2] 反应也首次成功应用于酰胺起始的富勒烯噁唑衍生物的合成。底物范围广泛，过程特别便宜和简单。