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遗传性多发性外生骨疣患者的前臂畸形:与活动范围和桡骨头脱位相关的因素。

Forearm deformity in patients with hereditary multiple exostoses: factors associated with range of motion and radial head dislocation.

机构信息

Department of Orthopaedics and Trauma, The Royal Infirmary of Edinburgh, Little France, Edinburgh EH16 4SA, Scotland, United Kingdom.

出版信息

J Bone Joint Surg Am. 2013 Sep 4;95(17):1586-92. doi: 10.2106/JBJS.L.00736.

Abstract

BACKGROUND

There is a high rate of forearm deformity in patients with hereditary multiple exostoses, with many patients developing radial head dislocation associated with ulnar shortening.

METHODS

One hundred and six patients with hereditary multiple exostoses who were fifteen years of age or older were identified with use of a previously compiled database. An independent observer measured flexion and extension of the elbow and wrist as well as supination and pronation of the forearm and recorded the number of exostoses affecting the forearm. Proportional ulnar length was calculated as a percentage of the measured height of the patient ([ulnar length/height] ×100).

RESULTS

Exostoses were identified in 183 (86%) of the 212 forearms that were examined. The distal part of the radius was the most common site and was affected in 73% of the patients. One in seven patients had a dislocated radial head, which was associated with reduced proportional ulnar length (p < 0.001). Both radial head dislocation (p < 0.001) and proportional ulnar length (p < 0.001) were confirmed to be independent risk factors associated with forearm rotation on multivariate regression analysis. In conjunction with other risk factors, both of these factors could be used to predict forearm motion. In addition, a reduced proportional ulnar length was also an independent risk factor for radial head dislocation (p < 0.001).

CONCLUSIONS

Proportional ulnar length could be used as a tool to identify patients who are at risk for diminished forearm motion and radial head dislocation during childhood. Surgical intervention could potentially be offered before deterioration in function and dislocation of the radial head occurs.

摘要

背景

遗传性多发外生骨疣患者前臂畸形发生率较高,很多患者出现桡骨头脱位,同时伴有尺骨缩短。

方法

使用先前编制的数据库,确定了 106 例年龄在 15 岁及以上的遗传性多发外生骨疣患者。一名独立观察者测量了患者肘部和腕部的屈伸以及前臂的旋前和旋后运动,并记录了影响前臂的外生骨数量。尺骨长度比例按患者身高的百分比计算([尺骨长度/身高]×100)。

结果

检查了 212 只前臂中的 183 只(86%)发现了外生骨。桡骨远端是最常见的受累部位,73%的患者受累。每 7 名患者中就有 1 名桡骨头脱位,与尺骨长度比例降低有关(p<0.001)。多变量回归分析证实,桡骨头脱位(p<0.001)和尺骨长度比例(p<0.001)均为与前臂旋转相关的独立危险因素。这两个因素与其他危险因素相结合,可以用来预测前臂运动。此外,尺骨长度比例降低也是桡骨头脱位的独立危险因素(p<0.001)。

结论

尺骨长度比例可作为一种工具,用于识别儿童时期前臂运动和桡骨头脱位风险增加的患者。在功能恶化和桡骨头脱位发生之前,可能需要进行手术干预。

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