Atherosclerosis: cell biology and lipoproteins.
作者信息
Lu Hong, Daugherty Alan
出版信息
Curr Opin Lipidol. 2013 Oct;24(5):455-6. doi: 10.1097/MOL.0b013e3283654ef9.
Abstract
摘要
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本文引用的文献
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Accelerating the pace of atherosclerosis research.加快动脉粥样硬化研究的步伐。
Arterioscler Thromb Vasc Biol. 2015 Jan;35(1):11-2. doi: 10.1161/ATVBAHA.114.304833.
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Induction of sustained hypercholesterolemia by single adeno-associated virus-mediated gene transfer of mutant hPCSK9.通过单腺相关病毒介导的突变型人前蛋白转化酶枯草溶菌素9基因转移诱导持续性高胆固醇血症
Arterioscler Thromb Vasc Biol. 2015 Jan;35(1):50-9. doi: 10.1161/ATVBAHA.114.303617. Epub 2014 Oct 23.
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Inhibition of PCSK9 with evolocumab in homozygous familial hypercholesterolaemia (TESLA Part B): a randomised, double-blind, placebo-controlled trial.依洛尤单抗抑制纯合子家族性高胆固醇血症（TESLA Part B）：一项随机、双盲、安慰剂对照试验。
Lancet. 2015 Jan 24;385(9965):341-50. doi: 10.1016/S0140-6736(14)61374-X. Epub 2014 Oct 1.
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PCSK9 R46L, lower LDL, and cardiovascular disease risk in familial hypercholesterolemia: a cross-sectional cohort study.PCSK9 R46L 降低 LDL 并增加家族性高胆固醇血症的心血管疾病风险：一项横断面队列研究。
Arterioscler Thromb Vasc Biol. 2014 Dec;34(12):2700-5. doi: 10.1161/ATVBAHA.114.304406. Epub 2014 Oct 2.
5
The proprotein convertase subtilisin/kexin type 9 (PCSK9) active site and cleavage sequence differentially regulate protein secretion from proteolysis.前蛋白转化酶枯草杆菌蛋白酶/kexin 9型（PCSK9）活性位点和切割序列对蛋白水解产生的蛋白质分泌具有不同的调节作用。
J Biol Chem. 2014 Oct 17;289(42):29030-43. doi: 10.1074/jbc.M114.594861. Epub 2014 Sep 10.
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A 52-week placebo-controlled trial of evolocumab in hyperlipidemia.依洛尤单抗治疗血脂异常的 52 周安慰剂对照试验。
N Engl J Med. 2014 May 8;370(19):1809-19. doi: 10.1056/NEJMoa1316222. Epub 2014 Mar 29.
7
Induction of atherosclerosis in mice and hamsters without germline genetic engineering.在不进行种系基因工程的情况下诱导小鼠和仓鼠发生动脉粥样硬化。
Circ Res. 2014 May 23;114(11):1684-9. doi: 10.1161/CIRCRESAHA.114.302937. Epub 2014 Mar 27.
8
Proprotein convertase subtilisin/kexin type 9 (PCSK9) can mediate degradation of the low density lipoprotein receptor-related protein 1 (LRP-1).前蛋白转化酶枯草溶菌素 9（PCSK9）可以介导低密度脂蛋白受体相关蛋白 1（LRP-1）的降解。
PLoS One. 2013 May 13;8(5):e64145. doi: 10.1371/journal.pone.0064145. Print 2013.
9
Development of experimental designs for atherosclerosis studies in mice.小鼠动脉粥样硬化研究实验设计的进展
Methods. 2005 Jun;36(2):129-38. doi: 10.1016/j.ymeth.2004.11.008.
10
Decreased plasma cholesterol and hypersensitivity to statins in mice lacking Pcsk9.缺乏Pcsk9的小鼠血浆胆固醇降低及对他汀类药物超敏反应
Proc Natl Acad Sci U S A. 2005 Apr 12;102(15):5374-9. doi: 10.1073/pnas.0501652102. Epub 2005 Apr 1.
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