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药物制剂中钾比色测定法可能干扰因素的研究。

A study of possible interferences in colorimetric determination of potassium in pharmaceutical formulations.

作者信息

Raggi M A, Nobile L, Ramini M, Perboni I

机构信息

Dipartimento di Scienze Farmaceutiche, Università di Bologna.

出版信息

Farmaco. 1990 Jun;45(6 Suppl):745-50.

PMID:2400524
Abstract

A study of interferences in the colorimetric determination of potassium, extracted as ion-pair [K-18-crown-6]+ picrate- in the toluene-methylene chloride (80:20) solvent mixture, was carried out. The species examined were those likely to be found, together with the K ion, in typical pharmaceutical formulations, namely, organic bases and inorganic cations.

摘要

开展了一项关于比色法测定钾时干扰情况的研究。钾以离子对[K - 18 - 冠 - 6]+苦味酸盐的形式在甲苯 - 二氯甲烷(80:20)混合溶剂中萃取。所检测的物质是那些在典型药物制剂中可能与钾离子一同存在的物质,即有机碱和无机阳离子。

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