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Tau pathology as a cause and consequence of the UPR.

作者信息

Stoveken Brian J

机构信息

University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229, USA.

出版信息

J Neurosci. 2013 Sep 4;33(36):14285-7. doi: 10.1523/JNEUROSCI.2961-13.2013.

DOI:10.1523/JNEUROSCI.2961-13.2013
PMID:24005281
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6618381/
Abstract
摘要

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本文引用的文献

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The unfolded protein response is activated in disease-affected brain regions in progressive supranuclear palsy and Alzheimer's disease.未折叠蛋白反应在进行性核上性麻痹和阿尔茨海默病的病变脑区被激活。
Acta Neuropathol Commun. 2013 Jul 6;1:31. doi: 10.1186/2051-5960-1-31.
2
Tau accumulation activates the unfolded protein response by impairing endoplasmic reticulum-associated degradation.tau 积聚通过损害内质网相关降解来激活未折叠蛋白反应。
J Neurosci. 2013 May 29;33(22):9498-507. doi: 10.1523/JNEUROSCI.5397-12.2013.
3
Tau pathology and neurodegeneration.tau 病理学与神经退行性变。
Lancet Neurol. 2013 Jun;12(6):609-22. doi: 10.1016/S1474-4422(13)70090-5.
4
Rapid accumulation of endogenous tau oligomers in a rat model of traumatic brain injury: possible link between traumatic brain injury and sporadic tauopathies.创伤性脑损伤大鼠模型中内源性 tau 寡聚体的快速积累：创伤性脑损伤与散发性 tau 病之间的可能联系。
J Biol Chem. 2013 Jun 7;288(23):17042-17050. doi: 10.1074/jbc.M113.472746. Epub 2013 Apr 30.
5
Unfolded protein response activates glycogen synthase kinase-3 via selective lysosomal degradation.未折叠蛋白反应通过选择性溶酶体降解激活糖原合酶激酶-3。
Neurobiol Aging. 2013 Jul;34(7):1759-71. doi: 10.1016/j.neurobiolaging.2013.01.008. Epub 2013 Feb 14.
6
Physiological release of endogenous tau is stimulated by neuronal activity.内源性 tau 的生理释放受神经元活动的刺激。
EMBO Rep. 2013 Apr;14(4):389-94. doi: 10.1038/embor.2013.15. Epub 2013 Feb 15.
7
Endoplasmic reticulum dysfunction in neurological disease.神经疾病中的内质网功能障碍。
Lancet Neurol. 2013 Jan;12(1):105-18. doi: 10.1016/S1474-4422(12)70238-7.
8
Endoplasmic reticulum stress induces tau pathology and forms a vicious cycle: implication in Alzheimer's disease pathogenesis.内质网应激诱导 tau 病理学并形成恶性循环：在阿尔茨海默病发病机制中的意义。
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Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy.鉴定影响tau 病进行性核上性麻痹风险的常见变异。
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