具有异常血浆生物标志物谱的急性HIV-1血清转化
Acute HIV-1 seroconversion with an unusual plasma biomarker profile.
作者信息
Aziz Najib, Detels Roger, Martinez-Maza Otoniel, Oishi John, Jamieson Beth D, Witt Mallory D, Butch Anthony W
机构信息
Department of Epidemiology, Fielding School of Public Health, University of California in Los Angeles, Los Angeles, California, USA.
出版信息
Clin Vaccine Immunol. 2013 Nov;20(11):1774-7. doi: 10.1128/CVI.00366-13. Epub 2013 Sep 4.
Abstract
An unusual case of acute primary HIV-1 infection in a man with a high plasma viral load, a 51-fold increase in C-reactive protein, and antibodies against only gp160 is described. Numerous serum cytokine concentrations were elevated during HIV-1 seroconversion.
摘要
描述了一名男性急性原发性HIV-1感染的罕见病例，其血浆病毒载量高，C反应蛋白增加51倍，且仅产生针对gp160的抗体。在HIV-1血清转化期间，多种血清细胞因子浓度升高。
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