大鼠血小板磷脂酶A2的基因组DNA结构。
Structure of genomic DNA for rat platelet phospholipase A2.
作者信息
Kusunoki C, Satoh S, Kobayashi M, Niwa M
机构信息
Bio-Technology Division, Fujisawa Pharmaceutical, Osaka, Japan.
出版信息
Biochim Biophys Acta. 1990 Sep 10;1087(1):95-7. doi: 10.1016/0167-4781(90)90127-n.
PMID:2400792
Abstract
A genomic DNA for rat platelet phospholipase A2 was isolated by screening a rat genomic library with oligonucleotide probes based on its published amino acid sequence. The rat platelet phospholipase A2 gene had a total length of about 2.5 kb and contained five exons and four introns. The intron-exon structure of the rate gene was similar to that of human non-pancreatic phospholipase A2.
摘要
通过使用基于已发表氨基酸序列的寡核苷酸探针筛选大鼠基因组文库，分离出大鼠血小板磷脂酶A2的基因组DNA。大鼠血小板磷脂酶A2基因全长约2.5 kb，包含5个外显子和4个内含子。大鼠基因的内含子-外显子结构与人类非胰腺磷脂酶A2的结构相似。
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