Chirila T V, Barrett G D, Russo A V, Constable I J, van Saarloos P P, Russo C I
Lions Eye Institute, Nedlands, Western Australia.
Biomaterials. 1990 Jul;11(5):313-20. doi: 10.1016/0142-9612(90)90107-2.
Commercial intraocular lenses and polymer specimens, both poly(methyl methacrylate) (PMMA) and poly(2-hydroxyethyl methacrylate) p(HEMA), were subjected to various levels of irradiation from a Q-switched Nd:YAG laser, and then to extraction and sample-enrichment techniques. The extracts were analysed by capillary gas chromatography. In PMMA samples, residual contents of 0.05-0.89% (wt) MMA were found and it appeared that the laser radiation did not cause a detectable increase of the monomer content. No residual HEMA could be found in p(HEMA) samples before or after laser bombardment. It is concluded that the accidental exposure of lenses to Nd:YAG laser cannot produce a significant release of monomers. Depolymerization induced by laser is a process unlikely to occur at the energy levels used in ophthalmic surgery.
对市售人工晶状体和聚合物样本（聚甲基丙烯酸甲酯（PMMA）和聚甲基丙烯酸2-羟乙酯p（HEMA））进行调Q Nd:YAG激光的不同剂量照射，然后采用萃取和样品富集技术处理。萃取物通过毛细管气相色谱法进行分析。在PMMA样品中，发现甲基丙烯酸甲酯（MMA）的残留含量为0.05 - 0.89%（重量），且激光辐射似乎并未导致单体含量出现可检测到的增加。在激光轰击前后，p（HEMA）样品中均未发现残留的HEMA。得出的结论是，人工晶状体意外暴露于Nd:YAG激光不会导致单体大量释放。在眼科手术所使用的能量水平下，激光诱导的解聚是一个不太可能发生的过程。
