Department of Forensic Medicine, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, Hubei 430030, PR China.
Forensic Sci Int. 2013 Oct 10;232(1-3):e9-11. doi: 10.1016/j.forsciint.2013.08.009. Epub 2013 Aug 19.
Systemic lupus erythematosus (SLE) is an autoimmune connective tissue disease affecting many organs and which is predominant in females. Although various manifestations of SLE may result in sudden death, pancarditis is very rarely encountered in forensic practice. We report on a case of sudden death caused by lupus-induced pancarditis. A 24-year-old male had pneumonia and intractable fever as initial signs when he was admitted to hospital. The patient had no symptoms associated with the cardiovascular system up to 3 days before he died. The echocardiogram and electrocardiogram were normal and diagnosis was not made until necropsy. This case is reported to broaden our understanding about the complexity of manifestations associated with SLE and inform clinicians and medical examiners of the potential for this type of lupus-induced pancarditis.
系统性红斑狼疮(SLE)是一种自身免疫性结缔组织疾病,可影响多个器官,且多见于女性。尽管 SLE 的各种表现都可能导致猝死,但在法医实践中极少见心肌炎。我们报告了一例狼疮性心肌炎引起的猝死病例。一名 24 岁男性因肺炎和高热入院,发病初期出现上述症状。患者在死亡前 3 天内没有出现任何与心血管系统相关的症状。超声心动图和心电图正常,直到尸检才做出诊断。本病例旨在提高我们对 SLE 相关表现复杂性的认识,并告知临床医生和法医检查人员注意这种狼疮性心肌炎的潜在风险。