Gallego R, Adrover E
Departamento de Fisiología, Universidad de Alicante, Spain.
Brain Res. 1990 Jul 23;523(2):298-300. doi: 10.1016/0006-8993(90)91501-7.
We have examined the effect of axotomy on the conduction velocity of unmyelinated sensory fibres in the vagus nerve of the rabbit. In an in vitro preparation of the nodose ganglion, conduction velocity was calculated for each cell from the latency of the intracellularly recorded action potential evoked by vagus nerve stimulation. The average velocity of sensory fibres conducting at less than 1.1 m/s, was 0.53 m/s in 287 control cells and 0.45 m/s in 269 neurones recorded 10 days after cutting the vagus nerve. Therefore, peripheral axotomy decreases conduction velocity in mammalian unmyelinated sensory axons.
我们研究了轴突切断术对家兔迷走神经中无髓鞘感觉纤维传导速度的影响。在体外制备的结节神经节中，根据迷走神经刺激诱发的细胞内记录动作电位的潜伏期，计算每个细胞的传导速度。传导速度小于1.1米/秒的感觉纤维，在287个对照细胞中的平均速度为0.53米/秒，在切断迷走神经10天后记录的269个神经元中的平均速度为0.45米/秒。因此，外周轴突切断术会降低哺乳动物无髓鞘感觉轴突的传导速度。
