Induced pluripotent stem cells from polycystic kidney disease patients: a novel tool to model the pathogenesis of cystic kidney disease.
作者信息
Hofherr Alexis, Köttgen Michael
机构信息
Renal Division, Department of Medicine, University Medical Centre Freiburg, Freiburg, Germany; and.
出版信息
J Am Soc Nephrol. 2013 Oct;24(10):1507-9. doi: 10.1681/ASN.2013070767. Epub 2013 Sep 5.
Abstract
摘要
相似文献
1
Induced pluripotent stem cells from polycystic kidney disease patients: a novel tool to model the pathogenesis of cystic kidney disease.来自多囊肾病患者的诱导多能干细胞：一种模拟囊性肾病发病机制的新工具。
J Am Soc Nephrol. 2013 Oct;24(10):1507-9. doi: 10.1681/ASN.2013070767. Epub 2013 Sep 5.
2
Another cystic mystery solved.
Nat Genet. 2002 Mar;30(3):247-8. doi: 10.1038/ng0302-247.
3
Generation of special autosomal dominant polycystic kidney disease iPSCs with the capability of functional kidney-like cell differentiation.生成具有功能性类肾细胞分化能力的特殊常染色体显性遗传性多囊肾病 iPSCs。
Stem Cell Res Ther. 2017 Sep 19;8(1):196. doi: 10.1186/s13287-017-0645-8.
4
Genetic studies: a key to understanding pathogenesis in PKD.
Nephrol News Issues. 2006 Dec;20(13):20-2.
5
Induced pluripotent stem cells derived from an autosomal dominant polycystic kidney disease patient carrying a PKD1 Q533X mutation.源自一名携带PKD1 Q533X突变的常染色体显性多囊肾病患者的诱导多能干细胞。
Stem Cell Res. 2017 Dec;25:83-87. doi: 10.1016/j.scr.2017.10.026. Epub 2017 Oct 28.
6
Cystic renal-epithelial derived induced pluripotent stem cells from polycystic kidney disease patients.来自多囊肾病患者的囊性肾上皮源性诱导多能干细胞。
Stem Cells Transl Med. 2020 Apr;9(4):478-490. doi: 10.1002/sctm.18-0283. Epub 2020 Mar 12.
7
ARPKD and ADPKD: first cousins or more distant relatives?常染色体隐性多囊肾病和常染色体显性多囊肾病：近亲还是远亲？
J Am Soc Nephrol. 2008 Mar;19(3):416-8. doi: 10.1681/ASN.2008010033. Epub 2008 Feb 13.
8
Generation of human induced pluripotent stem cell line (MUi026-A) from a patient with autosomal dominant polycystic kidney disease carrying PKD1 point mutation.从携带 PKD1 点突变的常染色体显性多囊肾病患者中生成人诱导多能干细胞系（MUi026-A）。
Stem Cell Res. 2021 May;53:102306. doi: 10.1016/j.scr.2021.102306. Epub 2021 Mar 22.
9
Recent advances in understanding ion transport mechanisms in polycystic kidney disease.对多囊肾病中离子转运机制的理解的最新进展。
Clin Sci (Lond). 2021 Nov 12;135(21):2521-2540. doi: 10.1042/CS20210370.
10
Sec63 and Xbp1 regulate IRE1α activity and polycystic disease severity.Sec63和Xbp1调节IRE1α活性和多囊性疾病严重程度。
J Clin Invest. 2015 May;125(5):1955-67. doi: 10.1172/JCI78863. Epub 2015 Apr 6.
引用本文的文献
1
Cystic kidney diseases associated with mutations in phosphomannomutase 2 promotor: a large spectrum of phenotypes.磷酸甘露糖变位酶 2 启动子突变相关的多囊肾病：表型谱广泛。
Pediatr Nephrol. 2021 Aug;36(8):2361-2369. doi: 10.1007/s00467-021-04953-9. Epub 2021 Feb 13.
2
Exploiting CRISPR Cas9 in Three-Dimensional Stem Cell Cultures to Model Disease.在三维干细胞培养中利用CRISPR Cas9技术模拟疾病
Front Bioeng Biotechnol. 2020 Jun 24;8:692. doi: 10.3389/fbioe.2020.00692. eCollection 2020.
3
GDNF drives rapid tubule morphogenesis in a novel 3D model for ADPKD.GDNF 驱动 ADPKD 新型 3D 模型中的快速小管形态发生。
J Cell Sci. 2020 Jul 16;133(14):jcs249557. doi: 10.1242/jcs.249557.
4
Directed differentiation of pluripotent stem cells to kidney cells.多能干细胞向肾细胞的定向分化。
Semin Nephrol. 2014 Jul;34(4):445-61. doi: 10.1016/j.semnephrol.2014.06.011. Epub 2014 Jun 13.
本文引用的文献
1
Reduced ciliary polycystin-2 in induced pluripotent stem cells from polycystic kidney disease patients with PKD1 mutations.多囊肾病患者 PKD1 突变诱导多能干细胞中纤毛多囊蛋白-2 减少。
J Am Soc Nephrol. 2013 Oct;24(10):1571-86. doi: 10.1681/ASN.2012111089. Epub 2013 Sep 5.
2
The promise of induced pluripotent stem cells in research and therapy.诱导多能干细胞在研究和治疗中的应用前景。
Nature. 2012 Jan 18;481(7381):295-305. doi: 10.1038/nature10761.
3
Successful disease-specific induced pluripotent stem cell generation from patients with kidney transplantation.成功地从肾移植患者中诱导出具有疾病特异性的多能干细胞。
Stem Cell Res Ther. 2011 Dec 6;2(6):48. doi: 10.1186/scrt89.
4
Modelling the long QT syndrome with induced pluripotent stem cells.利用诱导多能干细胞构建长 QT 综合征模型。
Nature. 2011 Mar 10;471(7337):225-9. doi: 10.1038/nature09747. Epub 2011 Jan 16.
5
Patient-specific induced pluripotent stem-cell models for long-QT syndrome.长 QT 综合征的患者特异性诱导多能干细胞模型。
N Engl J Med. 2010 Oct 7;363(15):1397-409. doi: 10.1056/NEJMoa0908679. Epub 2010 Jul 21.
6
What is the role of somatic mutation in autosomal dominant polycystic kidney disease?体细胞突变在常染色体显性多囊肾病中起什么作用？
J Am Soc Nephrol. 2010 Jul;21(7):1073-6. doi: 10.1681/ASN.2010030328. Epub 2010 May 20.
7
Molecular advances in autosomal dominant polycystic kidney disease.常染色体显性遗传性多囊肾病的分子进展。
Adv Chronic Kidney Dis. 2010 Mar;17(2):118-30. doi: 10.1053/j.ackd.2010.01.002.
8
Cystic disease of the kidney.肾囊性疾病
Annu Rev Pathol. 2007;2:341-68. doi: 10.1146/annurev.pathol.2.010506.091850.
9
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors.通过特定因子从小鼠胚胎和成体成纤维细胞培养物中诱导多能干细胞。
Cell. 2006 Aug 25;126(4):663-76. doi: 10.1016/j.cell.2006.07.024. Epub 2006 Aug 10.
10
Polycystin-2 traffics to cilia independently of polycystin-1 by using an N-terminal RVxP motif.多囊蛋白-2通过利用N端RVxP基序独立于多囊蛋白-1转运至纤毛。
J Cell Sci. 2006 Apr 1;119(Pt 7):1383-95. doi: 10.1242/jcs.02818. Epub 2006 Mar 14.
Zotero 插件