伴有间质细胞增生和绝经后男性化的乳腺卵巢转移瘤。

Mammary ovarian metastases with stroma cell hyperplasia and postmenopausal virilization.

作者信息

Caron P, Roche H, Gorguet B, Martel P, Bennet A, Carton M

机构信息

Service d'Endocrinologie, Clinique Dieulafoy, CHU Purpan, Toulouse, France.

出版信息

Cancer. 1990 Sep 15;66(6):1221-4. doi: 10.1002/1097-0142(19900915)66:6<1221::aid-cncr2820660623>3.0.co;2-b.

DOI:10.1002/1097-0142(19900915)66:6<1221::aid-cncr2820660623>3.0.co;2-b

PMID:2400972

Abstract

The case of a 57-year-old woman with a history of breast cancer is reported. She presented 10 years later with virilization. Stroma cell hyperplasia was present in the metastatic ovaries. The authors describe hormonal data and discuss the pathogenesis of the stromal activity. Mammary ovarian metastases associated with stroma cell hyperplasia, in the absence of pregnancy, that cause virilization are rare.

摘要

报告了一例有乳腺癌病史的57岁女性病例。10年后她出现男性化症状。转移性卵巢中存在间质细胞增生。作者描述了激素数据并讨论了间质活性的发病机制。在非妊娠情况下，与间质细胞增生相关且导致男性化的乳腺卵巢转移很少见。