Key Laboratory of Analytical Chemistry for Biology and Medicine (Ministry of Education), College of Chemistry and Molecular Sciences, Research Center for Nanobiology and Nanomedicine (MOE 985 Innovative Platform), Wuhan Institute of Biotechnology, and State Key Laboratory of Virology, Wuhan University, Wuhan, 430072, P. R. China.
Analyst. 2013 Nov 7;138(21):6301-4. doi: 10.1039/c3an01282d.
We present a low background, highly selective and amplified fluorescent sensor for potassium ions using graphene oxide (GO) and a cationic conjugated polymer (CCP). This method takes advantage of the phenomenon that the addition of CCP cannot release the dye labeled guanine-rich DNA from the GO surface, and the conformational switch of the guanine-rich DNA from random coil to G-quadruplex induced by the target.
我们提出了一种使用氧化石墨烯（GO）和阳离子共轭聚合物（CCP）的钾离子低背景、高选择性和高灵敏荧光传感器。该方法利用了这样一种现象，即加入 CCP 不能从 GO 表面释放出标记有鸟嘌呤丰富 DNA 的染料，以及目标诱导的鸟嘌呤丰富 DNA 从无规线团到 G-四链体的构象转换。
