Man Chaolai, Zhen Xin, Tang Gaoxia, Zhao Li, Li Feng, Mi Xiaoju
Key Laboratory of Molecular Cytogenetics and Genetic Breeding of Heilongjiang Province, College of Life Science and Technology, Harbin Normal University, Harbin 150025, Heilongjiang, China.
Sheng Wu Gong Cheng Xue Bao. 2013 May;29(5):578-85.
microRNAs (miRNAs) are a family of important small non-coding RNA molecules, which participate in the post transcriptional gene regulation. In this review, the numbers and chromosomal distribution of chicken miRNAs, and the regulation and function of chicken miRNAs in immune, embryo development and virus infection were reviewed. Additionally, the applications of chicken miRNAs were also discussed briefly. We hope it can provide references for further study and use of miRNAs in poultry husbandry fields.
微小RNA(miRNA)是一类重要的小型非编码RNA分子,它们参与转录后基因调控。在本综述中,对鸡miRNA的数量和染色体分布,以及鸡miRNA在免疫、胚胎发育和病毒感染中的调控及功能进行了综述。此外,还简要讨论了鸡miRNA的应用。我们希望它能为家禽养殖领域中miRNA的进一步研究和应用提供参考。