Department of Molecular, Cellular, and Biomedical Sciences, University of New Hampshire, 46 College Road, Durham, NH 03824-2617, USA.
Can J Microbiol. 2013 Sep;59(9):627-40. doi: 10.1139/cjm-2013-0343. Epub 2013 Aug 12.
Found widespread around the globe, Serratia are Gram-negative bacteria capable of thriving in a diverse number of environments that include water, soil, and the digestive tracts of various animals. Known for their ability to produce a myriad of extracellular enzymes, these bacteria also produce various secondary metabolites that directly contribute to their survival. While the effects Serratia species have on other organisms range from parasitic to symbiotic, what these bacteria have in common is their ability to resist attack, respond appropriately to environmental conditions, and outcompete other microorganisms when colonizing their respective niche. This review highlights the mechanisms utilized by Serratia species that drive their ubiquitous nature, with emphasis on the latest findings. Also discussed is how secreted compounds drive these bacteria towards pathogenic, mutualistic, and antagonistic associations.
普遍存在于全球各地的沙雷氏菌是革兰氏阴性细菌,能够在包括水、土壤和各种动物的消化道在内的多种环境中茁壮成长。它们以能够产生大量细胞外酶而闻名,还能产生各种有助于生存的次级代谢物。虽然沙雷氏菌对其他生物体的影响从寄生到共生不等,但这些细菌的共同点是它们具有抵抗攻击、对环境条件做出适当反应以及在定殖各自小生境时胜过其他微生物的能力。本综述强调了驱动沙雷氏菌普遍存在的机制,重点介绍了最新的发现。还讨论了分泌的化合物如何促使这些细菌形成致病、共生和拮抗关系。