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[前往热带地区旅行者中的盘尾丝虫病]

[Onchocerciasis in travelers to the tropics].

作者信息

Junghanss T, Weiss N

机构信息

Schweizerisches Tropeninstitut, Basel.

出版信息

Dtsch Med Wochenschr. 1990 Sep 14;115(37):1392-6. doi: 10.1055/s-2008-1065169.

Abstract

Two men, aged 54 and 31 years respectively, developed an itching skin rash 18 and 6 months respectively after returning from a trip to Africa, the former also recurrent conjunctivitis. Two years and 6 months, respectively, passed from the time of first symptoms until the diagnosis of onchocerciasis was made. Both patients had an eosinophilia (10.5 and 19%) and specific antibodies against Onchocerca volvulus. Microfilaria were demonstrated in the skin of the younger man. The other one had bilateral corneal infiltrates. Both patients were treated with a single dose of ivermectin, 150 micrograms/kg. Within several months, the clinical symptoms and eosinophilia disappeared and the antibody titres decreased.

摘要

两名男子,年龄分别为54岁和31岁,在从非洲旅行归来后分别于18个月和6个月出现皮肤瘙痒性皮疹,前者还伴有复发性结膜炎。从首次出现症状到诊断为盘尾丝虫病分别过去了两年和6个月。两名患者均有嗜酸性粒细胞增多(分别为10.5%和19%)以及抗盘尾丝虫的特异性抗体。在较年轻男子的皮肤中发现了微丝蚴。另一名患者有双侧角膜浸润。两名患者均接受了单剂量伊维菌素治疗,剂量为150微克/千克。数月内,临床症状和嗜酸性粒细胞增多消失,抗体滴度下降。

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