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原位结合发酵和双极膜电渗析生产乳酸:连续操作。

In-situ combination of fermentation and electrodialysis with bipolar membranes for the production of lactic acid: continuous operation.

机构信息

CAS, Key Laboratory of Soft Matter Chemistry, Laboratory of Functional Membranes, School of Chemistry and Materials Science, University of Science and Technology of China, Hefei, Anhui 230026, People's Republic of China.

CAS, Key Laboratory of Soft Matter Chemistry, Laboratory of Functional Membranes, School of Chemistry and Materials Science, University of Science and Technology of China, Hefei, Anhui 230026, People's Republic of China.

出版信息

Bioresour Technol. 2013 Nov;147:442-448. doi: 10.1016/j.biortech.2013.08.045. Epub 2013 Aug 14.

DOI:10.1016/j.biortech.2013.08.045
PMID:24012733
Abstract

An experimental study was carried out to achieve a continuous integrated operation of fermentation and electrodialysis with bipolar membranes (EDBM). There need three steps to accomplish this experiment: (1) individual continuous fermentation; (2) individual continuous EDBM; (3) integrated operation of fermentation and EDBM under continuous condition. The results indicate that the maximum feed rate (fermenter can afford) is 0.24 L/h, which is also equal to the feed rate of the subsequent individual continuous EDBM. During continuous EDBM, the recovery ratio of lactate from the fermentation broth can reach 69.5% under a current density of 40 mA/cm(2). The net end concentration and total molar quantity for lactic acid can reach 1.46 mol/L and 2.18 mol, and for OH(-) are 1.32 mol/L and 1.70 mol, respectively. The integration can be achieved only under an initial alkali concentration of no less than 1 mol/L and a current density of no less than 30 mA/cm(2).

摘要

进行了一项实验研究,以实现发酵和双极膜电渗析(EDBM)的连续集成操作。完成该实验需要三个步骤:(1)单独的连续发酵;(2)单独的连续 EDBM;(3)在连续条件下进行发酵和 EDBM 的集成操作。结果表明,最大进料速率(发酵罐能够承受的速率)为 0.24 L/h,这也等于后续单独连续 EDBM 的进料速率。在连续 EDBM 过程中,在 40 mA/cm(2)的电流密度下,发酵液中乳酸的回收率可达 69.5%。净末端浓度和乳酸的总摩尔量分别达到 1.46 mol/L 和 2.18 mol,而 OH(-)分别达到 1.32 mol/L 和 1.70 mol。只有在初始碱浓度不低于 1 mol/L 和电流密度不低于 30 mA/cm(2)的情况下才能实现集成。

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