交感神经系统实验性肿瘤的形态学
Morphology of experimental tumors of the sympathetic nervous system.
作者信息
Beniashvili D S
机构信息
Experimental Oncology Department, Georgian SSR Ministry of Health, Tbilissi.
出版信息
Exp Pathol. 1990;39(2):89-94. doi: 10.1016/s0232-1513(11)80165-9.
The morphology of experimental tumors of the sympathetic nervous system in rabbits and hamsters induced by administration of nitrose compounds and the use of modifying factors were studied. The tumors were localized in the mediastinum, retroperitoneal space, adrenals and kidneys. A predominant involvement of the female animals was observed. Histological, histochemical and electron microscopic studies of 33 tumors of the sympathetic nervous system were carried out. By their degree of maturity the tumors were classified as ganglioneuromas, ganglioneuroblastomas and neuroblastomas. By their structure the experimental tumors were similar to the analogous neoplasias of man.
研究了给予亚硝基化合物并使用修饰因子诱导的兔和仓鼠交感神经系统实验性肿瘤的形态学。肿瘤位于纵隔、腹膜后间隙、肾上腺和肾脏。观察到雌性动物受累为主。对33例交感神经系统肿瘤进行了组织学、组织化学和电子显微镜研究。根据成熟程度，肿瘤分为神经节瘤、神经节神经母细胞瘤和神经母细胞瘤。从结构上看，实验性肿瘤与人的类似肿瘤相似。
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