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氯丙嗪诱导的肝和骨髓肉芽肿伴粒细胞缺乏症。

Chlorpromazine-induced liver and bone marrow granulomas associated with agranulocytosis.

作者信息

Ben-Yehuda A, Bloom A, Lijovetzky G, Flusser D, Tur-Kaspa R

机构信息

Department of Medicine, Hadassah University Hospital, Jerusalem, Israel.

出版信息

Isr J Med Sci. 1990 Aug;26(8):449-51.

PMID:2401609
Abstract

Chlorpromazine-induced liver damage is usually manifested by intrahepatic cholestasis. Hypoplastic bone marrow associated with agranulocytosis is a well-known side effect of chlorpromazine treatment. A 35-year-old woman with liver and bone marrow granulomas associated with agranulocytosis induced by chlorpromazine treatment is described.

摘要

氯丙嗪引起的肝损伤通常表现为肝内胆汁淤积。与粒细胞缺乏症相关的骨髓发育不全是氯丙嗪治疗众所周知的副作用。本文描述了一名35岁女性,其患有与氯丙嗪治疗引起的粒细胞缺乏症相关的肝脏和骨髓肉芽肿。

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