Wang Xin-hua, Zhang Hong, Guo Li-min, Miao Ke-jun, DA Wen-ping, Wu Bin, Xu Da-qin, Ge Ya-jun, Mu Tao-xia, Chen Guo-juan, Zhou Xiao-yan, Wang Shi-ming, Ge Peng-fei, Xi Jin-xiao
Gansu Provincial Centre for Disease Control and Prevention, Lanzhou, China.
Zhonghua Liu Xing Bing Xue Za Zhi. 2013 May;34(5):433-7.
To study the genotype distributions and epidemiological characteristics of Yersinia pestis in Gansu province.
Primers were designed according to the confirmed 23 differential sections, to genotype the 202 Yersinia pestis DNA of Gansu province by PCR, and to analyze its distribution and epidemiological characteristics.
Yersinia pestis in Gansu province could be divided into eight genotypes: 1b, 5, 7, 8, 13, 26, new genotype 1 (GS1) and new genotype 2 (GS2). They were distributed in various regions. 1b, 8 and GS1 genotypes of Yersinia pestis had been identified since 1960s but the 7, 13 and 26 genotypes had not been isolated for more than 40 years while GS2 and 5 genotypes had been isolated since 1990s.
1b, 8 and GS1 genotypes of Yersinia pestis continued to be violently prevalent since 1960s but 7, 13 and 26 genotypes had not been isolated for more than 40 years while GS2 and 5 genotypes had started to be popular since 1990s.
研究甘肃省鼠疫耶尔森菌的基因分型分布及流行病学特征。
根据已确认的23个差异区段设计引物，采用聚合酶链反应（PCR）对甘肃省202株鼠疫耶尔森菌DNA进行基因分型，并分析其分布及流行病学特征。
甘肃省鼠疫耶尔森菌可分为8种基因型：1b、5、7、8、13、26、新基因型1（GS1）和新基因型2（GS2）。它们分布于不同地区。鼠疫耶尔森菌的1b、8和GS1基因型自20世纪60年代起已被鉴定出来，而7、13和26基因型已40多年未分离到，GS2和5基因型自20世纪90年代起已被分离到。
鼠疫耶尔森菌的1b、8和GS1基因型自20世纪60年代起持续高度流行，而7、13和26基因型已40多年未分离到，GS2和5基因型自20世纪90年代起开始流行。
