Németh Zsuzsanna, Boér Katalin, Kásler Miklós, Borbély Katalin
Szent Margit Kórház Onkológiai Osztály Budapest Bécsi út 132. 1032.
Orv Hetil. 2013 Sep 15;154(37):1447-53. doi: 10.1556/OH.2013.29700.
Modern imaging techniques have an important role in the diagnostic procedures of malignancies, and assessing response to therapy. The 18F-FDG PET/CT revolutionized the evaluation of colorectal cancer in terms of preoperative staging and monitoring of recurrence. Conventional imaging techniques have limitations in early assessment of response to therapy. 18F-FDG PET has been shown to allow earlier treatment monitoring, because the metabolic change appears before any anatomic change occurs. The Response Evaluation Criteria in Solid Tumours (RECIST) are widely applied, but they have some limitations. There are new international guidelines for treatment response assessment using PET/CT in solid tumours. The authors review indications and the role of hybrid PET/CT in colorectal cancer.
现代成像技术在恶性肿瘤的诊断程序以及评估治疗反应中发挥着重要作用。18F-FDG PET/CT在结直肠癌的术前分期和复发监测方面彻底改变了评估方式。传统成像技术在早期评估治疗反应方面存在局限性。18F-FDG PET已被证明能够实现更早的治疗监测,因为代谢变化在任何解剖学变化出现之前就已发生。实体瘤疗效评价标准(RECIST)被广泛应用,但也存在一些局限性。对于实体瘤使用PET/CT进行治疗反应评估有新的国际指南。作者回顾了PET/CT在结直肠癌中的应用指征及作用。