Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.
Kaohsiung J Med Sci. 2013 Sep;29(9):469-77. doi: 10.1016/j.kjms.2012.10.007. Epub 2013 Jan 12.
Early diagnosis and severity evaluation in patients with acute pancreatitis (AP) are very important due to its potential morbidity and mortality. Several clinical, laboratory, and radiologic factors, and many scoring systems have been proposed for outcome prediction. Although the Ranson and Acute Physiology and Chronic Health Evaluation II scoring systems have been widely used for decades, the cumbersome components partly limit their predictability. Recently, the Bedside Index for Severity in AP scoring system and series blood urea nitrogen changes, which are simple and convenient to evaluate within 24 hours after admission, have been validated for accuracy by several large-cohort studies. The presence of organ failure and systemic inflammatory response syndrome are also helpful to evaluate the severity of AP. Herein we review recent advances of the predictive methods for AP to provide an up-to-date perspective on outcome assessment of AP.
由于急性胰腺炎（AP）具有潜在的发病率和死亡率，因此早期诊断和严重程度评估非常重要。已经提出了几种临床、实验室和影像学因素以及许多评分系统来预测预后。虽然 Ranson 和急性生理学和慢性健康评估 II 评分系统已经使用了几十年，但繁琐的组成部分部分限制了它们的预测能力。最近，床边 AP 严重程度评分系统和一系列血尿素氮变化已经在几项大型队列研究中得到验证，这些方法简单方便，可以在入院后 24 小时内进行评估。器官衰竭和全身炎症反应综合征的存在也有助于评估 AP 的严重程度。本文综述了 AP 预测方法的最新进展，为 AP 的预后评估提供了最新视角。
