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患有喉软化症儿童的漏斗胸

Pectus excavatum in children with laryngomalacia.

作者信息

Schaerer Daniel, Virbalas Jordan, Willis Elena, Siegel Bianca, Gonik Nathan, Bent John

机构信息

Albert Einstein College of Medicine, Montefiore Medical Center, United States.

出版信息

Int J Pediatr Otorhinolaryngol. 2013 Oct;77(10):1721-3. doi: 10.1016/j.ijporl.2013.07.033. Epub 2013 Aug 14.

Abstract

BACKGROUND

Laryngomalacia is the most common congenital laryngeal anomaly and is associated with several disorders including gastric reflux, sleep apnea, hypotonia and failure to thrive. Pectus excavatum (PE) is the most common chest wall deformity affecting 1-300/1000 individuals. Though many authors presume a relationship between PE and laryngomalacia, there is no published data to establish this association.

GOAL

To test the hypothesis that patients referred to our pediatric otolaryngology clinic for evaluation of laryngomalacia exhibit higher rates of PE than the general population.

METHODS

Retrospective review of prospectively enrolled children who presented with laryngomalacia (January 2008-June 2012) to a tertiary care, hospital based, pediatric otolaryngology practice. Each chart was examined for a concurrent diagnosis of pectus deformity.

RESULTS

Of the 137 laryngomalacia patients, 9 (6.6%) had documented PE. This represents a significantly increased rate of PE when compared to children without laryngomalacia (p = 0.001). Four of the 9 children with PE underwent supraglottoplasty for laryngomalacia, a significantly greater proportion than the 9/128 of the children with isolated laryngomalacia who underwent supraglottoplasty (p = 0.004).

CONCLUSIONS

This study suggests an association between laryngomalacia and PE. Pediatric otolaryngologists should be cognizant of this relationship, though further studies are needed to elucidate the nature of this association.

摘要

背景

喉软化是最常见的先天性喉部异常,与多种疾病相关,包括胃食管反流、睡眠呼吸暂停、肌张力减退和生长发育迟缓。漏斗胸(PE)是最常见的胸壁畸形,每1000人中就有1 - 300人受其影响。尽管许多作者推测PE与喉软化之间存在关联,但尚无已发表的数据证实这种关联。

目的

检验以下假设:因喉软化前来我们儿科耳鼻喉科诊所评估的患者中,PE的发生率高于普通人群。

方法

对2008年1月至2012年6月前瞻性纳入的患有喉软化的儿童进行回顾性研究,这些儿童来自一家三级医疗、以医院为基础的儿科耳鼻喉科诊所。检查每份病历,以确定是否同时诊断出胸壁畸形。

结果

在137例喉软化患者中,9例(6.6%)有记录显示患有PE。与无喉软化的儿童相比,这代表着PE的发生率显著增加(p = 0.001)。9例患有PE的儿童中有4例因喉软化接受了声门上成形术,这一比例显著高于仅患有喉软化且接受声门上成形术的儿童中的9/128(p = 0.004)。

结论

本研究表明喉软化与PE之间存在关联。儿科耳鼻喉科医生应认识到这种关系,不过仍需进一步研究以阐明这种关联的本质。

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