Pokrywczyńska Marta, Jundziłł Arkadiusz, Adamowicz Jan, Drewa Tomasz
Zakład Inżynierii Tkankowej, Uniwersytet Mikołaja Kopernika, Bydgoszcz.
Postepy Hig Med Dosw (Online). 2013 Aug 6;67:790-9. doi: 10.5604/17322693.1061633.
The most common cause of bladder reconstruction is radical cystectomy for invasive bladder cancer. Currently, bowel segments remains, the most widely used in reconstruction of urinary tract. Using of bowel as a "material" for bladder reconstruction is associated with numerous complications. Tissue engineering methods provide opportunities to construct bladder tissue in vitro from autologous cells obtained from non urinary tract system. So far, the most useful cell and matrix type for bladder reconstruction have not been defined. In this work actual knowledge about tissue engineering in bladder regeneration was presented.
膀胱重建最常见的原因是对浸润性膀胱癌进行根治性膀胱切除术。目前,肠段仍然是尿路重建中使用最广泛的材料。将肠用作膀胱重建的“材料”会引发诸多并发症。组织工程方法为利用从非泌尿系统获取的自体细胞在体外构建膀胱组织提供了机会。到目前为止,用于膀胱重建的最有用的细胞和基质类型尚未确定。在这项工作中,介绍了关于膀胱再生中组织工程的实际知识。