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重症监护中被认为无效的治疗的频率和成本。

The frequency and cost of treatment perceived to be futile in critical care.

机构信息

Division of Pulmonary and Critical Care Medicine, Department of Medicine, David Geffen School of Medicine, University of California Los Angeles.

出版信息

JAMA Intern Med. 2013 Nov 11;173(20):1887-94. doi: 10.1001/jamainternmed.2013.10261.

Abstract

IMPORTANCE

Physicians often perceive as futile intensive care interventions that prolong life without achieving an effect that the patient can appreciate as a benefit. The prevalence and cost of critical care perceived to be futile have not been prospectively quantified.

OBJECTIVE

To quantify the prevalence and cost of treatment perceived to be futile in adult critical care.

DESIGN, SETTING, AND PARTICIPANTS: To develop a common definition of futile care, we convened a focus group of clinicians who care for critically ill patients. On a daily basis for 3 months, we surveyed critical care specialists in 5 intensive care units (ICUs) at an academic health care system to identify patients whom the physicians believed were receiving futile treatment. Using a multivariate model, we identified patient and clinician characteristics associated with patients perceived to be receiving futile treatment. We estimated the total cost of futile treatment by summing the charges of each day of receiving perceived futile treatment and converting to costs.

MAIN OUTCOME AND MEASURE

Prevalence of patients perceived to be receiving futile treatment.

RESULTS

During a 3-month period, there were 6916 assessments by 36 critical care specialists of 1136 patients. Of these patients, 904 (80%) were never perceived to be receiving futile treatment, 98 (8.6%) were perceived as receiving probably futile treatment, 123 (11%) were perceived as receiving futile treatment, and 11 (1%) were perceived as receiving futile treatment only on the day they transitioned to palliative care. The patients with futile treatment assessments received 464 days of treatment perceived to be futile in critical care (range, 1-58 days), accounting for 6.7% of all assessed patient days in the 5 ICUs studied. Eighty-four of the 123 patients perceived as receiving futile treatment died before hospital discharge and 20 within 6 months of ICU care (6-month mortality rate of 85%), with survivors remaining in severely compromised health states. The cost of futile treatment in critical care was estimated at $2.6 million.

CONCLUSIONS AND RELEVANCE

In 1 health system, treatment in critical care that is perceived to be futile is common and the cost is substantial.

摘要

重要性

医生经常认为,延长生命而没有达到患者可以认为是受益的效果的重症监护干预是徒劳的。尚未前瞻性地量化被认为是徒劳的重症监护的流行率和成本。

目的

量化成人重症监护中被认为是徒劳的治疗的流行率和成本。

设计、地点和参与者:为了制定一个关于徒劳治疗的共同定义,我们召集了一组照顾重症患者的临床医生进行焦点小组讨论。在 3 个月的时间里,我们每天在一个学术医疗保健系统的 5 个重症监护病房(ICU)中调查重症监护专家,以确定医生认为正在接受徒劳治疗的患者。使用多变量模型,我们确定了与被认为接受徒劳治疗的患者相关的患者和临床医生特征。我们通过将每天接受被认为是徒劳治疗的费用相加并转换为成本来估计徒劳治疗的总成本。

主要结果和措施

被认为接受徒劳治疗的患者的患病率。

结果

在 3 个月的时间里,有 36 名重症监护专家对 1136 名患者进行了 6916 次评估。在这些患者中,904 名(80%)从未被认为接受过徒劳治疗,98 名(8.6%)被认为接受过可能的徒劳治疗,123 名(11%)被认为接受过徒劳治疗,11 名(1%)仅在转入姑息治疗的当天被认为接受了徒劳治疗。接受徒劳治疗评估的患者在重症监护中接受了 464 天的治疗,被认为是徒劳的(范围为 1-58 天),占研究的 5 个 ICU 中所有评估患者天数的 6.7%。在 123 名被认为接受徒劳治疗的患者中,84 名在出院前死亡,20 名在 ICU 护理后 6 个月内死亡(6 个月死亡率为 85%),幸存者仍处于严重受损的健康状态。重症监护中徒劳治疗的成本估计为 2600 万美元。

结论和相关性

在一个医疗系统中,被认为是徒劳的重症监护治疗很常见,成本也很高。

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