Hong S S, Ogawa Y, Yagi T, Wakasa K, Sakurai M, Sato M, Harada T
Department of Oral Pathology, Osaka University Medical School, Japan.
J Oral Pathol Med. 1990 Jul;19(6):266-70. doi: 10.1111/j.1600-0714.1990.tb00839.x.
A case of benign lymphoepithelial lesion with two large cysts and many foci of duct dilatation is reported. Clinical features, except for absence of dry eyes, indicated the case was Sjögren's syndrome. The cysts were found in the left parotid gland of a 60-yr-old woman and were surgically removed. The size of each cyst was 20 mm in diameter and one of them was located in the lymph node. Because of the HLA-DR expression by the epithelium, the cysts are considered to have formed as a result of duct dilatation due to autoimmune response. As for one cyst, it is also possible that the pre-existing lymphoepithelial cyst might be involved in the autoimmune phenomenon because of its relation to the lymph node.
报告了一例伴有两个大囊肿和多个导管扩张灶的良性淋巴上皮病变。临床特征除无干眼外,提示该病例为干燥综合征。囊肿发现于一名60岁女性的左腮腺,已通过手术切除。每个囊肿直径为20毫米,其中一个位于淋巴结内。由于上皮细胞表达HLA - DR,这些囊肿被认为是自身免疫反应导致导管扩张而形成的。至于其中一个囊肿,由于其与淋巴结的关系,也有可能先前存在的淋巴上皮囊肿参与了自身免疫现象。