Verma Priyanka, Hephzibah Julie, Shanthly Nylla, Oommen Regi
Department of Nuclear Medicine, Christian Medical College, Vellore, Tamil Nadu, India.
Indian J Nucl Med. 2012 Oct;27(4):246-8. doi: 10.4103/0972-3919.115396.
Radiolabelled metaiodobenzylguanidine (MIBG) is commonly used for imaging of neuroendocrine tumors (NETs). The hybrid imaging with single photon emission computerized tomography/computerized tomography (SPECT/CT) co-registration can give that additional edge to this functional imaging modality.
To study the additional value of (131)I-MIBG SPECT/CT scintigraphy in evaluation of NETs.
We performed a retrospective study of the scintigraphic data of patients referred to our department for detection and follow-up of NETs from 2004 to 2008.
Total number of studies were 370. Twenty-eight patients with equivocal findings on planar imaging had undergone additional SPECT/CT imaging. The contribution made by SPECT/CT imaging in these studies was analyzed.
In 27 of 28 cases, SPECT/CT provided vital additional information.
We concluded that SPECT/CT co-registration helps in exclusion, identification, and localization of primary and metastatic NETs. It differentiates physiological from pathological tracer distribution. It helps increase the confidence in reporting, especially in equivocal findings on planar imaging.
放射性标记的间碘苄胍(MIBG)常用于神经内分泌肿瘤(NETs)的成像。单光子发射计算机断层扫描/计算机断层扫描(SPECT/CT)共配准的混合成像可为这种功能成像方式提供额外优势。
研究¹³¹I-MIBG SPECT/CT闪烁扫描在评估NETs中的附加价值。
我们对2004年至2008年转诊至我科进行NETs检测和随访的患者的闪烁扫描数据进行了回顾性研究。
研究总数为370例。28例平面成像结果不明确的患者接受了额外的SPECT/CT成像。分析了这些研究中SPECT/CT成像的贡献。
28例中的27例,SPECT/CT提供了至关重要的额外信息。
我们得出结论,SPECT/CT共配准有助于原发性和转移性NETs的排除、识别和定位。它能区分生理性与病理性示踪剂分布。它有助于提高报告的可信度,尤其是在平面成像结果不明确的情况下。