创伤后胶质瘤：一例报告。

Spallone Aldo, Izzo Chiara, Orlandi Augusto

Section of Neurosurgery, Department of Clinical Neurosciences, Neurological Centre of Latium 'NCL', Rome, Italy ; Department of Biopathology, Institute of Anatomical Pathology, Tor Vergata University of Rome, Rome, Italy.

Case Rep Oncol. 2013 Aug 7;6(2):403-9. doi: 10.1159/000354340. eCollection 2013.

For a long time, head injury has been considered as a possible causative factor for later development of brain tumors. However, the actual role of previous head trauma in the pathogenesis of intracranial tumors is still a matter of debate, also due to the possible medico-legal implications. Some authors have suggested several criteria for establishing a possible causal relationship between the aforementioned factors. We report a case of a left posterior paraventricular high-grade glioma which developed 20 years after a posttraumatic hematoma occurring in the same area. This case is reported in detail and the relevant literature is reviewed.

长期以来，头部损伤一直被认为是脑肿瘤后期发展的一个可能致病因素。然而，既往头部外伤在颅内肿瘤发病机制中的实际作用仍存在争议，这也归因于可能涉及的医疗法律问题。一些作者提出了若干标准，以确定上述因素之间可能存在的因果关系。我们报告一例左后脑室旁高级别胶质瘤病例，该肿瘤在同一区域创伤后血肿发生20年后出现。本文详细报告了该病例并对相关文献进行了综述。