Kano Osamu, Okonogi Shinichi, Hanashiro Sayori, Miura Ken, Ikeda Ken, Iwasaki Yasuo
Department of Neurology, Toho University Omori Medical Center, Tokyo, Japan.
Case Rep Neurol. 2013 Aug 28;5(2):139-42. doi: 10.1159/000354980. eCollection 2013.
Benign tremulous parkinsonism (BTP) is a tremor dominant syndrome characterized by mild, levodopa-resistant parkinsonism with limited disability or progression.
A 56-year-old woman presented with a 2-year history of tremor. Neurological examination revealed right-hand rest tremor and slow finger tapping with decreased amplitude; however, we did not observe posture tremor, rigidity, bradykinesia, or posture disability. She was diagnosed with Parkinson's disease (PD) and received levodopa/carbidopa, effectively treating her rest tremor. At the age of 61 years, reoccurrence of the rest tremor was successfully treated again with levodopa/carbidopa and selegiline. Approximately 11 years have passed since symptom onset and the patient shows no further disease progression.
This case broadens the characterization of BTP to include levodopa-responsive PD.
良性震颤性帕金森综合征（BTP）是一种以震颤为主的综合征，其特征为轻度、左旋多巴抵抗性帕金森综合征，残疾或病情进展有限。
一名56岁女性，有2年震颤病史。神经系统检查发现右手静止性震颤和手指叩击缓慢且幅度减小；然而，我们未观察到姿势性震颤、强直、运动迟缓或姿势性残疾。她被诊断为帕金森病（PD）并接受了左旋多巴/卡比多巴治疗，有效治疗了她的静止性震颤。61岁时，静止性震颤复发，再次使用左旋多巴/卡比多巴和司来吉兰成功治疗。自症状出现以来大约已过去11年，患者未显示出进一步的疾病进展。
该病例拓宽了BTP的特征，将左旋多巴反应性PD纳入其中。
