Research and Innovation Centre, Fondazione Edmund Mach (FEM), Via E. Mach 1, San Michele all'Adige 38010, Italy.
Sensors (Basel). 2013 Sep 9;13(9):11923-55. doi: 10.3390/s130911923.
Proton Transfer Reaction Mass Spectrometry (PTR-MS) has evolved in the last decade as a fast and high sensitivity sensor for the real-time monitoring of volatile compounds. Its applications range from environmental sciences to medical sciences, from food technology to bioprocess monitoring. Italian scientists and institutions participated from the very beginning in fundamental and applied research aiming at exploiting the potentialities of this technique and providing relevant methodological advances and new fundamental indications. In this review we describe this activity on the basis of the available literature. The Italian scientific community has been active mostly in food science and technology, plant physiology and environmental studies and also pioneered the applications of the recently released PTR-ToF-MS (Proton Transfer Reaction-Time of Flight-Mass Spectrometry) in food science and in plant physiology. In the very last years new results related to bioprocess monitoring and health science have been published as well. PTR-MS data analysis, particularly in the case of the ToF based version, and the application of advanced chemometrics and data mining are also aspects characterising the activity of the Italian community.
质子转移反应质谱（PTR-MS）在过去十年中发展成为一种快速、高灵敏度的传感器，可用于实时监测挥发性化合物。其应用范围从环境科学到医学科学，从食品技术到生物过程监测。意大利科学家和机构从一开始就参与了基础和应用研究，旨在利用该技术的潜力，并提供相关的方法学进展和新的基本指示。在这篇综述中，我们根据现有文献描述了这一活动。意大利科学界主要活跃在食品科学与技术、植物生理学和环境研究领域，并率先将最近发布的 PTR-ToF-MS（质子转移反应-飞行时间质谱）应用于食品科学和植物生理学。在过去的几年中，也发表了与生物过程监测和健康科学相关的新成果。PTR-MS 数据分析，特别是基于飞行时间的版本，以及先进的化学计量学和数据挖掘的应用，也是意大利研究社区的特点。
