Knoll D, Kirchhoff P G, Nordbeck H, Orellano L, Radke J, Regensburger D, Schaper J, Schlemminger H, Spieckermann P G
Thoraxchir Vask Chir. 1975 Jun;23(3):313-7. doi: 10.1055/s-0028-1096971.
In a total of 16 patients the tissue pH was determined on myocardium both during surgery and on isolated samples. Cardiac arrest was induced by hypothermal infusion cardioplegia and external cooling. In the isolated human myocardium section pH values were continuously determined at 15 degrees C. Parallel to these measurements samples were taken for electron microscopic examinations. In this way the pH limit under which the human myocardium cannot be revived could be visualized by additional morphologic examination. These results and those from the intrasurgical measurements with a fixed heart muscle surface probe were compared with each other and with results from animal experiments.
共有16例患者,在手术过程中和离体样本上测定了心肌组织的pH值。通过低温灌注心脏停搏液和外部降温诱导心脏停搏。在15℃下连续测定离体人心肌切片的pH值。在进行这些测量的同时,采集样本进行电子显微镜检查。通过额外的形态学检查,可以观察到人类心肌无法复苏的pH极限。将这些结果与手术中使用固定心肌表面探头测量的结果以及动物实验的结果进行了相互比较。