前瞻性比例作为老年人早期认知障碍语言障碍的指标。
The anticipatory proportion as an indicator of language impairment in early-stage cognitive disorder in the elderly.
机构信息
Department of Internal Medicine and Cardiology, Charité - Universitätsmedizin Berlin, Berlin, Germany.
出版信息
Dement Geriatr Cogn Disord. 2013;36(5-6):300-9. doi: 10.1159/000350808. Epub 2013 Sep 6.
BACKGROUND
The anticipatory proportion (AP), the ratio between perseverative and anticipatory speech errors, is reduced in patients with brain injury. However, it is unknown whether the AP is also reduced in elderly speakers with cognitive impairment.
METHODS
20 elderly speakers with a Mini Mental State Examination (MMSE) score of 25-27 and 20 elderly speakers with an MMSE score of 28-30 were assessed using a tongue-twister-based speech test, the Regensburg Word Fluency Test (RWT) and an object naming test.
RESULTS
The AP in the group of speakers with an MMSE score of 25-27 was significantly lower. Accordingly, the AP and scores in the RWT and the object naming test were higher in persons with an MMSE score of 28-30.
CONCLUSION
Language alterations in mild cognitive dysfunction are detectable with the AP. Further longitudinal studies are needed to evaluate the predictive value of the AP.
背景
前瞻性比例（AP），即持续和预期言语错误之间的比例，在脑损伤患者中降低。然而，目前尚不清楚认知障碍的老年患者的 AP 是否也会降低。
方法
使用绕口令为基础的言语测试、雷根斯堡单词流畅性测试（RWT）和物体命名测试评估了 20 名 MMSE 评分为 25-27 的老年患者和 20 名 MMSE 评分为 28-30 的老年患者。
结果
MMSE 评分为 25-27 的患者的 AP 明显较低。因此，MMSE 评分为 28-30 的患者的 AP 和 RWT 及物体命名测试的分数更高。
结论
轻度认知功能障碍的语言改变可以通过 AP 检测到。需要进一步的纵向研究来评估 AP 的预测价值。
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