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Autoxidation of N-hydroxyamphetamine and N-hydroxyphentermine. The formation of 2-nitroso-1-phenyl-propanes and 1-phenyl-2-propanone oxime.

作者信息

Lindeke B, Anderson E

出版信息

Acta Pharm Suec. 1975;12(2):183-98.

PMID:240248
Abstract
摘要

相似文献

1
Autoxidation of N-hydroxyamphetamine and N-hydroxyphentermine. The formation of 2-nitroso-1-phenyl-propanes and 1-phenyl-2-propanone oxime.
Acta Pharm Suec. 1975;12(2):183-98.
2
Autoxidation of N-hydroxyphenylalkylamines: the inhibitory effect of some anions on copper catalysed autoxidation of N-hydroxyphentermine.
J Pharm Pharmacol. 1977 Jun;29(6):358-62. doi: 10.1111/j.2042-7158.1977.tb11335.x.
3
N-oxidation of phentermine to N-hydroxyphentermine by a reconstituted cytochrome P-450 oxidase system from rabbit liver.
Mol Pharmacol. 1982 Sep;22(2):235-8.
4
The opposing effects of N-hydroxyamphetamine and N-hydroxyphentermine on the H2O2 generated by hepatic cytochrome P-450.
Mol Pharmacol. 1982 Sep;22(2):465-70.
5
Synthesis, analysis and mutagenic activity of N-nitroso derivatives of glycosylamines and Amadori compounds: nitrosated model substances for the early Maillard reaction products.糖基胺和阿玛多利化合物的N-亚硝基衍生物的合成、分析及诱变活性：早期美拉德反应产物的亚硝化模型物质
IARC Sci Publ. 1987(84):277-83.
6
The oxidation of N-hydroxyphentermine by various oxidase systems.
Proc West Pharmacol Soc. 1979;22:105-7.
7
Identification of a nitrone as an in vitro metabolite of N-methylamphetamine.鉴定一种硝酮为N-甲基苯丙胺的体外代谢物。
Biomed Mass Spectrom. 1978 Jun;5(6):418-22. doi: 10.1002/bms.1200050609.
8
[Formation of carcinogenic N-nitroso compounds in vivo and in the human environment].
Vopr Onkol. 1980;26(10):92-6.
9
Mechanism of oxidation of N-hydroxyphentermine by superoxide.
Biochemistry. 1985 Jul 16;24(15):4161-7. doi: 10.1021/bi00336a052.
10
The reduction of certain C-nitroso compounds by rat liver cytosol.
Res Commun Chem Pathol Pharmacol. 1973 Jul;6(1):151-65.

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Importance of H-abstraction in the final step of nitrosoalkane formation in the mechanism-based inactivation of cytochrome P450 by amine-containing drugs.亚硝烷形成过程中 H 原子迁移在含胺药物致细胞色素 P450 酶系失活反应机制中的重要性。
Int J Mol Sci. 2013 Dec 18;14(12):24692-705. doi: 10.3390/ijms141224692.
2
Preparations of C-nitroso compounds.C-亚硝基化合物的制备。
Chem Rev. 2004 Jul;104(7):3315-40. doi: 10.1021/cr030450k.
3
The metabolism and binding of catecholamines by the hepatic microsomal mixed-function oxidase of the rat.
大鼠肝脏微粒体混合功能氧化酶对儿茶酚胺的代谢及结合作用。
Biochem J. 1976 Jul 15;158(1):135-40. doi: 10.1042/bj1580135.