从塔玛亚历山大藻中分离出的一种莫拉克斯氏菌属细菌产生麻痹性贝类毒素。

Production of paralytic shellfish toxins by a bacterium Moraxella sp. isolated from Protogonyaulax tamarensis.

作者信息

Kodama M, Ogata T, Sakamoto S, Sato S, Honda T, Miwatani T

机构信息

Laboratory of Marine Biological Chemistry, School of Fisheries Sciences, Kitasato University, Iwate, Japan.

出版信息

Toxicon. 1990;28(6):707-14. doi: 10.1016/0041-0101(90)90259-a.

DOI:10.1016/0041-0101(90)90259-a

PMID:2402764

Abstract

A bacterium Moraxella sp. isolated from Protogonyaulax tamarensis was cultured in various conditions. Changes of toxicity and toxin components of the cells during culture were analyzed by bioassay and HPLC-fluorometric analysis. Toxin productivity of Moraxella sp. increased when it was cultured in nutrition-deficient environments. The main toxins produced by Moraxella sp. in these conditions were gonyautoxins (GTXs), mainly GTX 1 and 4 which are major toxins of P. tamarensis.

摘要

从塔玛亚历山大藻（Protogonyaulax tamarensis）中分离出的一种莫拉克斯氏菌（Moraxella sp.）在各种条件下进行培养。通过生物测定和高效液相色谱 - 荧光分析，分析了培养过程中细胞毒性和毒素成分的变化。莫拉克斯氏菌在营养缺乏环境中培养时，其毒素产生能力增强。在此条件下，莫拉克斯氏菌产生的主要毒素是膝沟藻毒素（GTXs），主要为GTX 1和4，它们是塔玛亚历山大藻的主要毒素。