Neumann L, Mikkelsen P M, Madsen M S, Andersen J A
Odense Sygehus, ortopaedkirurgisk afdeling O, og.
Ugeskr Laeger. 1990 Sep 3;152(36):2550-2.
A questionnaire about prophylactic antibiotic treatment of open bone, tendon or joint lesions in the extremities was sent to the 83 casualty departments in Denmark. The questionnaire was answered by 56 casualty departments which treated 72% of the orthopaedic surgical injuries in Denmark. In cases of lesions of the hands and feet, 23% of the patients were treated in casualty departments where prophylactic antibiotic therapy was rarely employed while 24% were treated in casualty departments where prophylactic antibiotic therapy was always employed. In cases of lesions proximal to the wrist or ankle joints, the figures were 26% and 38%, respectively. Penicillin was nearly always employed and treatment was commenced before or during operation. The majority of departments continued treatment for four days or longer. Considerable scatter was reported in the dosage of penicillin employed. The literature about prophylactic antibiotic treatment in cases of complicated lesions of the extremities is insufficient and controlled investigations are necessary to elucidate a series of conditions.
一份关于四肢开放性骨骼、肌腱或关节损伤预防性抗生素治疗的调查问卷被发送给丹麦的83个急诊科。56个急诊科回复了问卷,这些科室处理了丹麦72%的骨科手术损伤。在手足损伤病例中,23%的患者在很少使用预防性抗生素治疗的急诊科接受治疗,而24%的患者在总是使用预防性抗生素治疗的急诊科接受治疗。在腕关节或踝关节近端损伤的病例中,这两个数字分别为26%和38%。几乎总是使用青霉素,且在手术前或手术期间开始治疗。大多数科室持续治疗四天或更长时间。据报告,所用青霉素剂量存在很大差异。关于四肢复杂损伤预防性抗生素治疗的文献不足,需要进行对照研究以阐明一系列情况。