Faculdade União das Américas, , Foz do Iguaçu, Paraná, Brazil.
Acupunct Med. 2013 Dec;31(4):358-63. doi: 10.1136/acupmed-2013-010394. Epub 2013 Sep 12.
The objective of this investigation was to evaluate the effects of acupuncture and sham acupuncture on the symptoms of anxiety and depression brought on by premenstrual dysphoric disorder (PMDD).
In a single-blind randomised clinical trial, 30 volunteers with PMDD were assigned alternately to group 1 (acupuncture) or group 2 (sham acupuncture), and completed an evaluation of symptoms of anxiety and depression using the Hamilton Anxiety (HAM-A) and Hamilton Depression (HAM-D) Rating Scales. The procedure was performed twice a week for two menstrual cycles, for a total of 16 attendances for each participant.
Before the intervention the mean HAM-A and HAM-D scores did not differ between groups. Following the intervention symptoms of anxiety and depression were reduced in both groups; however, the improvement was significant in group 1 compared to group 2, as shown by a mean reduction in HAM-A scores of 58.9% in group 1 and 21.2% in group 2 (p<0.001). The reduction in the mean HAM-D scores was 52.0% in group 1 and 19.6% in group 2, resulting in a significant difference (p=0.012).
The results suggest that acupuncture could be another treatment option for PMDD patients.
本研究旨在评估针刺和假针刺对经前期烦躁障碍（PMDD）引起的焦虑和抑郁症状的影响。
在一项单盲随机临床试验中，将 30 名 PMDD 志愿者交替分配至第 1 组（针刺）或第 2 组（假针刺），并使用汉密尔顿焦虑量表（HAM-A）和汉密尔顿抑郁量表（HAM-D）对焦虑和抑郁症状进行评估。每周两次进行治疗，共进行两个月经周期，每位参与者共进行 16 次就诊。
干预前，两组的 HAM-A 和 HAM-D 评分无差异。干预后，两组的焦虑和抑郁症状均有所减轻；但第 1 组的改善明显优于第 2 组，HAM-A 评分的平均降幅分别为 58.9%和 21.2%（p<0.001）。HAM-D 评分的平均降幅分别为 52.0%和 19.6%，差异具有统计学意义（p=0.012）。
研究结果表明，针刺可能是 PMDD 患者的另一种治疗选择。
