KU Leuven Department of Development and Regeneration, Leuven, Belgium.
Eur J Obstet Gynecol Reprod Biol. 2013 Nov;171(1):154-6. doi: 10.1016/j.ejogrb.2013.08.029. Epub 2013 Aug 19.
To investigate whether the pattern or pain or bleeding during levonorgestrel intrauterine system (LNG-IUS) insertion and in the first 6 weeks thereafter is altered by LNG-IUS malposition.
Prospective cohort of 413 women undergoing LNG-IUS insertion or replacement. A first questionnaire on pain perception was completed by the women immediately after insertion. In a second questionnaire the women were asked to record pain in the 3 days following insertion and both pain and bleeding from 4 to 6 weeks after insertion. Six weeks after insertion a 2D- and 3D-ultrasound examination was performed to evaluate the position of the LNG-IUS and of the uterus.
Parity was inversely related to pain at insertion, in the first 3 days and at 4-6 weeks. LNG-IUS insertion was less painful in the postpartum period. Women who had had a LNG-IUS as prior contraceptive method reported a higher percentage of amenorrhea at 4-6 weeks. The position of the LNG-IUS or of the uterus did not influence the pain scores or the bleeding pattern. The fact that the LNG-IUS arms appeared embedded in the uterine wall on coronal 3D-volume reconstruction did not influence pain or the bleeding pattern.
Because neither pain nor bleeding is a reliable predictor of LNG-IUS position, we suggest an ultrasound examination to confirm correct LNG-IUS placement in all patients at about 6 weeks after insertion.
探讨左炔诺孕酮宫内节育系统(LNG-IUS)放置后及放置后 6 周内的疼痛或出血模式是否因 LNG-IUS 位置不当而改变。
对 413 名接受 LNG-IUS 插入或更换的妇女进行前瞻性队列研究。女性在插入后立即完成关于疼痛感知的第一个问卷。在第二个问卷中,女性被要求记录插入后 3 天内的疼痛,以及插入后 4 至 6 周内的疼痛和出血情况。插入后 6 周时,进行二维和三维超声检查以评估 LNG-IUS 和子宫的位置。
产次与插入时、前 3 天和 4-6 周时的疼痛呈负相关。产后 LNG-IUS 插入时疼痛较轻。曾使用 LNG-IUS 作为避孕方法的女性在 4-6 周时报告闭经的比例更高。LNG-IUS 或子宫的位置并不影响疼痛评分或出血模式。在冠状 3D 容积重建中,LNG-IUS 臂似乎嵌入子宫壁的事实并不影响疼痛或出血模式。
由于疼痛或出血都不是 LNG-IUS 位置的可靠预测因素,我们建议在插入后约 6 周对所有患者进行超声检查以确认 LNG-IUS 的正确位置。