埃塞俄比亚西部贝德莱祖里亚县基于社区的足分支菌病调查。

Community-based survey of podoconiosis in Bedele Zuria woreda, west Ethiopia.

作者信息

Tekola Ayele Fasil, Alemu Getahun, Davey Gail, Ahrens Christel

机构信息

Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Building 12A, Room 4044, 12 South Drive, Bethesda, MD 20892, USA.

出版信息

Int Health. 2013 Jun;5(2):119-25. doi: 10.1093/inthealth/iht003.

DOI:10.1093/inthealth/iht003

PMID:24030111

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3889643/

Abstract

BACKGROUND

Podoconiosis is a neglected tropical disease resulting in progressive bilateral swelling of the lower legs in barefoot individuals exposed to red-clay soil derived from volcanic rocks. It is a considerable public health problem in countries across tropical Africa, Central America and northern India. The present study aimed to assess the prevalence and clinical features of podoconiosis, and patients' experience of disease prevention and treatment, in Bedele Zuria woreda (district), west Ethiopia.

METHODS

The study was conducted during 2011 and involved a house-to-house survey in all 2285 households of five randomly selected rural kebeles (villages).

RESULTS

The prevalence of podoconiosis was 5.6% (379/6710) (95% CI 5.1-6.2%) and was significantly greater among women than men (6.6% vs 4.7%; p = 0.001). A total of 311 (16.9%) households had at least one member with podoconiosis, and 128 (33.8%) study participants reported having a blood relative with podoconiosis. Two hundred and forty-three (76.4%) podoconiosis patients were in the economically productive age group of 15-64 years. On average, a patient experienced at least six episodes of adenolymphangitis per year resulting in a loss of 25 working days per year.

CONCLUSION

This study has revealed a high burden of podoconiosis in west Ethiopia, and suggests that disease prevention and treatment programmes are needed.

摘要

背景

足分支菌病是一种被忽视的热带疾病，会导致赤脚接触源自火山岩的红粘土的人双下肢逐渐肿胀。在热带非洲、中美洲和印度北部的国家，这是一个相当严重的公共卫生问题。本研究旨在评估埃塞俄比亚西部贝德莱祖里亚县（区）足分支菌病的患病率和临床特征，以及患者在疾病预防和治疗方面的经历。

方法

该研究于2011年进行，对随机选取的5个农村社区（村庄）的所有2285户家庭进行了逐户调查。

结果

足分支菌病的患病率为5.6%（379/6710）（95%置信区间5.1 - 6.2%），女性患病率显著高于男性（6.6%对4.7%；p = 0.001）。共有311户（16.9%）家庭至少有一名成员患有足分支菌病，128名（33.8%）研究参与者报告有患足分支菌病的血亲。243名（76.4%）足分支菌病患者处于15 - 64岁的经济生产年龄组。平均而言，一名患者每年至少经历6次腺淋巴管炎发作，导致每年损失25个工作日。