From the *State University of New York at Stony Brook, Stony Brook; and †Winthrop Rheumatology, Allergy & Immunology, Mineola, NY.
Dermatitis. 2013 Sep-Oct;24(5):205-14. doi: 10.1097/DER.0b013e3182a0d38a.
Adverse drug reactions occur commonly and primarily manifest in a myriad of cutaneous eruptions. The use of drug patch testing in the diagnosis of specific drug eruptions is increasing; however, a standardized approach to this methodology is currently lacking. A review of current literature was performed on the available evidence of patch testing for drugs. This review addresses the use of patch testing for specific cutaneous adverse drug reactions and for specific classes of drugs including antimicrobials, anticonvulsants, antiretrovirals, glucocorticoids, and nonsteroidal anti-inflammatory drugs. In addition, the approach to performing patch testing to drugs in the clinical arena as well as current contraindications for drug patch testing is reviewed.
药物不良反应很常见，主要表现为各种皮肤疹。药物斑贴试验在特定药物疹的诊断中应用越来越多；然而，目前这种方法缺乏标准化。对现有药物斑贴试验证据进行了文献复习。本综述讨论了斑贴试验在特定皮肤药物不良反应和特定类别的药物中的应用，包括抗生素、抗惊厥药、抗逆转录病毒药物、糖皮质激素和非甾体抗炎药。此外，还回顾了在临床环境中进行药物斑贴试验的方法以及药物斑贴试验的当前禁忌症。
