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用于广泛胸主动脉手术的双动脉灌注策略,以避免下半身低温循环骤停。

Double arterial perfusion strategy for extensive thoracic aortic surgery to avoid lower body hypothermic circulatory arrest.

作者信息

Czerny Martin, Mach Markus, Schönhoff Florian, Basciani Reto, Jenni Hansjörg, Carrel Thierry P, Schmidli Jürg

机构信息

Department of Cardiovascular Surgery, University Hospital Berne, Berne, Switzerland.

出版信息

Eur J Cardiothorac Surg. 2014 Mar;45(3):460-5. doi: 10.1093/ejcts/ezt449. Epub 2013 Sep 12.

Abstract

OBJECTIVE

To analyse our results of using a double arterial perfusion strategy to avoid lower body hypothermic circulatory arrest after extensive thoracic aortic surgery.

METHODS

We analysed the intra- and perioperative courses of 10 patients (median age 58 years, median logistic EuroSCORE 14.6) who underwent extensive thoracic aortic surgery with a double arterial perfusion strategy. The main goal of double arterial perfusion is to separate myocardial and supra-aortic from systemic perfusion. Aortic repair starts at the most distal level of the descending aorta, followed by reinsertion of the supra-aortic vessels, and ends with completion of the proximal anastomosis or by any kind of root repair as needed.

RESULTS

Seven of 10 patients had prior surgery of the thoracic aorta. Indications for surgery were post-dissection aneurysm in 4 patients, true aneurysm in 3, anastomotic aneurysms in 2 and Type B aortic dissection with pseudo-coarctation in 1. Surgical access was performed through median sternotomy with left hemi-clamshell extension in all cases. There was no in-hospital mortality, but perioperative neurological symptoms occurred in 2 patients. These 2 patients developed delayed stroke (after awaking) after an initial uneventful clinical course, and in 1 of them, neurological symptoms resolved completely during follow-up. The median follow-up was 7 (± 13) months. There was no death and no need for additional redo surgery during this observational period.

CONCLUSIONS

Extensive surgery of the thoracic aorta using a double arterial perfusion technique in order to avoid lower body hypothermic circulatory arrest is an attractive option. Further refinements of this technique may enable the safe and effective simultaneous multisegmental treatment of thoracic aortic pathology in patients who would otherwise have to undergo a two-step surgical approach.

摘要

目的

分析我们采用双动脉灌注策略避免广泛胸主动脉手术后下半身低温循环骤停的结果。

方法

我们分析了10例(中位年龄58岁,中位逻辑欧洲心脏手术风险评估系统评分为14.6)接受广泛胸主动脉手术并采用双动脉灌注策略患者的术中和围手术期过程。双动脉灌注的主要目的是将心肌和主动脉上灌注与全身灌注分开。主动脉修复从降主动脉最远端开始,随后重新植入主动脉上血管,最后完成近端吻合或根据需要进行任何类型的根部修复。

结果

10例患者中有7例曾接受过胸主动脉手术。手术适应证为4例夹层后动脉瘤、3例真性动脉瘤、2例吻合口动脉瘤和1例B型主动脉夹层伴假性缩窄。所有病例均通过正中胸骨切开术加左半蛤壳式延长进行手术入路。无院内死亡,但2例患者出现围手术期神经症状。这2例患者在最初临床过程平稳后出现延迟性卒中(苏醒后),其中1例患者在随访期间神经症状完全缓解。中位随访时间为7(±13)个月。在此观察期内无死亡,也无需进行额外的再次手术。

结论

采用双动脉灌注技术进行广泛的胸主动脉手术以避免下半身低温循环骤停是一种有吸引力的选择。该技术的进一步改进可能使原本需要分两步手术的患者能够安全有效地同时进行胸主动脉病变的多节段治疗。

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