Zaouak A, Benmously R, Belhadj Salah M, Koubaa W, Debbiche A, Mokhtar I
Service de dermatologie, faculté de médecine de Tunis, université de Tunis-El-Manar, hôpital Habib-Thameur, 8, rue Ali-Ben-Ayed-Montfleury, 1008 Tunis, Tunisie.
Ann Dermatol Venereol. 2013 Aug-Sep;140(8-9):540-3. doi: 10.1016/j.annder.2013.04.095. Epub 2013 May 30.
Perineuriomas are tumours derived from the perineurial cells of the neural sheath. Soft tissue perineuriomas are rare. Herein, we report a case of perineurioma localized to the nose.
A 24-year-old adult presented with a cutaneous nodule 1cm in diameter localized on the nose. Histologically, the tumour corresponded to a well-circumscribed fusocellular dermal proliferation organized in a storiform pattern. After surgical removal, the lesion did not recur.
Extraneural soft tissue perineurioma is usually a benign nerve sheath tumour composed mainly of perineurial cells. Our case occurred in a 24-year-old Caucasian adult. The tumour generally presents as a unique cutaneous nodule corresponding histologically to a well-delineated dermal fusocellular proliferation organized in a storiform pattern that stains positive for EMA and negative for S100. The tumour is usually localized to the trunk and extremities. Location on the nose as in our patient has been rarely reported. Surgical removal of the tumour is the treatment of choice.
神经束膜瘤是起源于神经鞘膜神经束膜细胞的肿瘤。软组织神经束膜瘤罕见。在此，我们报告一例局限于鼻部的神经束膜瘤病例。
一名24岁成年人，鼻部出现一个直径1厘米的皮肤结节。组织学检查显示，肿瘤为边界清楚的梭形细胞真皮增生，呈车辐状排列。手术切除后，病变未复发。
神经外软组织神经束膜瘤通常是一种主要由神经束膜细胞组成的良性神经鞘瘤。我们的病例发生在一名24岁的白种成年人身上。该肿瘤通常表现为单个皮肤结节，组织学上对应于边界清晰的真皮梭形细胞增生，呈车辐状排列，上皮膜抗原（EMA）染色阳性，S100染色阴性。肿瘤通常局限于躯干和四肢。像我们患者这样发生在鼻部的情况鲜有报道。手术切除肿瘤是首选治疗方法。
