[法国泌尿外科学会传染病委员会及法国泌尿外科学会神经泌尿学委员会指南：骶神经调节的抗生素预防]
[Guidelines from the Infectious Disease Committee of the French Association of Urology and The Neuro-Urology Committee of the AFU: antibiotic prophylaxis for sacral neuromodulation].
作者信息
Doublet J D, Sotto A, Escaravage L, Vérine J L, Conquy S, Cariou G, Coloby P, Malavaud S, Boiteux J P, Thibault M, Bugel H, Gamé X, Karsenty G, Ruffion A, Bruyère F
机构信息
Service d'urologie, CHU de Bretonneau, 2, boulevard Tonnellé, 37044 Tours, France.
出版信息
Prog Urol. 2013 Sep;23(10):849-55. doi: 10.1016/j.purol.2013.04.018. Epub 2013 Jun 2.
INTRODUCTION
In urology, antibiotic prophylaxis is advised by the French Association of anesthesiology (SFAR) and the Infectious Disease Committee of the French Association of urology guidelines published in 2010. No guideline exists concerning the implantation of neuromodulation implants.
MATERIAL AND METHOD
A literature analysis was performed on sacral modulation and antibiotic prophylaxis. Then guidelines were discussed by reviewers. Items that showed no consensus were then discussed again to arrive at recommendations.
RESULTS
Antibiotic prophylaxis is recommended during the test phase as well as in the case of installation of sacral neuromodulation (Grade C). Antibiotic recommended (Grade B) are: cefotetan or cefoxitin, 2g dose by slow intravenous injection or amoxicillin-clavulanic acid at a dose of 2 g, intravenously or, in the case of allergy vancomycin at a dose of 15 mg/kg or the clindamycin has 600 mg intravenously.
CONCLUSIONS
Despite the lack of high level of evidence, antibiotic prophylaxis seems necessary when setting up of electrode case of sacral neuromodulation.
引言
在泌尿外科领域，法国麻醉学会（SFAR）和法国泌尿外科学会传染病委员会在2010年发布的指南中建议使用抗生素预防。目前尚无关于神经调节植入物植入的指南。
材料与方法
对骶神经调节和抗生素预防进行了文献分析。然后由评审人员讨论指南。对未达成共识的项目再次进行讨论以得出建议。
结果
在测试阶段以及骶神经调节植入时均建议使用抗生素预防（C级）。推荐的抗生素（B级）为：头孢替坦或头孢西丁，2克剂量缓慢静脉注射，或阿莫西林 - 克拉维酸2克剂量静脉注射，或在过敏情况下使用15毫克/千克剂量的万古霉素或600毫克静脉注射的克林霉素。
结论
尽管缺乏高水平证据，但在骶神经调节电极植入时抗生素预防似乎是必要的。
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